Compound
methanol
A colorless, flammable liquid used in the manufacture of formaldehyde and acetic acid, in chemical synthesis, antifreeze, and as a solvent. Ingestion of methanol is toxic and may cause blindness.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- CH4O
- Mass
- 32.042 g/mol
- Charge
- 0
- InChIKey
- OKKJLVBELUTLKV-UHFFFAOYSA-N
- SMILES
- CO
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
16 entities
16 entities reached.
0 reported hops16 assembled from the scaffold
- CATProteinUNIPROT:P04040substrate ofInferred only34 paths34 endpoints
- PRDX6ProteinUNIPROT:P30041substrate ofInferred only30 paths15 endpoints
- ADH1AProteinUNIPROT:P07327metabolized byInferred only17 paths17 endpoints
- ADH5ProteinUNIPROT:P11766metabolized byInferred only16 paths16 endpoints
- PXDNProteinUNIPROT:Q92626substrate ofInferred only14 paths14 endpoints
- ADH4ProteinUNIPROT:P08319metabolized byInferred only14 paths14 endpoints
- MPOProteinUNIPROT:P05164substrate ofInferred only13 paths13 endpoints
- ADH7ProteinUNIPROT:P40394metabolized byInferred only12 paths12 endpoints
- ADH1CProteinUNIPROT:P00326metabolized byInferred only11 paths11 endpoints
- ADH1BProteinUNIPROT:P00325metabolized byInferred only10 paths10 endpoints
- LPOProteinUNIPROT:P22079substrate ofInferred only10 paths5 endpoints
- EPXProteinUNIPROT:P11678substrate ofInferred only6 paths3 endpoints
What the reference databases state
Statements
26 statements
26 statements · 2 reference databases · Subject: methanol · Sources: Human-GEM, Rhea
- methanol is converted to formaldehydeCompoundHuman-GEM MAR04201Inferred only
- formaldehyde is converted to methanolCompoundRhea RHEA:19401Inferred only
- methanol is converted to formaldehydeCompoundHuman-GEM MAR04202Inferred only
- formaldehyde is converted to methanolCompoundRhea RHEA:30691Inferred only
- methanol is converted to formaldehydeCompoundHuman-GEM MAR08752Inferred only
- methanol is converted to formaldehydeCompoundRhea RHEA:19401Inferred only
- methanol is converted to formaldehydeCompoundRhea RHEA:30691Inferred only
- methanol is metabolised by ADH1AProteinHuman-GEM MAR04202Inferred only
- methanol is metabolised by ADH1BProteinHuman-GEM MAR04202Inferred only
- methanol is metabolised by ADH1CProteinHuman-GEM MAR04202Inferred only
- methanol is metabolised by ADH4ProteinHuman-GEM MAR04202Inferred only
- methanol is metabolised by ADH5ProteinHuman-GEM MAR04202Inferred only
Show the remaining 14
- methanol is metabolised by ADH6ProteinHuman-GEM MAR04202Inferred only
- methanol is metabolised by ADH7ProteinHuman-GEM MAR04202Inferred only
- methanol is a substrate of ADHFE1ProteinHuman-GEM MAR04202Inferred only
- methanol is a substrate of CATProteinHuman-GEM MAR04201Inferred only
- methanol is a substrate of DPH7ProteinRhea RHEA:42656Inferred only
- methanol is a substrate of EPXProteinHuman-GEM MAR08752Inferred only
- methanol is a substrate of EPXProteinHuman-GEM MAR04201Inferred only
- methanol is a substrate of LPOProteinHuman-GEM MAR08752Inferred only
- methanol is a substrate of LPOProteinHuman-GEM MAR04201Inferred only
- methanol is a substrate of MPOProteinHuman-GEM MAR08752Inferred only
- methanol is a substrate of PPME1ProteinRhea RHEA:48548Inferred only
- methanol is a substrate of PRDX6ProteinHuman-GEM MAR08752Inferred only
- methanol is a substrate of PRDX6ProteinHuman-GEM MAR04201Inferred only
- methanol is a substrate of PXDNProteinHuman-GEM MAR04201Inferred only
Reactions
60 reactions
hydrogen peroxide+methanolformaldehyde+2water
Catalysed by PRDX6 or EPX or CAT or PXDN or LPO
Reaction pageLeft to rightBalancedEC 1.11.1.6, 1.11.1.7cytosol
Human-GEM MAR04201CC BY 4.0Reference data
methanol+NAD(+)formaldehyde+proton+NADH(2-)
Catalysed by ADHFE1 or ADH6 or ADH1A or ADH7 or ADH1B or ADH5 or ADH4 or ADH1C
Reaction pageLeft to rightBalancedEC 1.1.1.244cytosol
Human-GEM MAR04202CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05296CC BY 4.0Reference data
MAM01344c+proton+NADPH(4-)+0.5dioxygenMAM01768c+methanol+NADP(3-)
Catalysed by CYP2C18
Reaction pageLeft to rightBalancedEC 1.14.14.1cytosol
Human-GEM MAR08043CC BY 4.0Reference data
ecgonine methyl ester+waterCHEBI:708641+proton+methanol
Catalysed by AADAC
Reaction pageLeft to rightBalancedEC 3.1.1.3endoplasmic reticulum
Human-GEM MAR08648CC BY 4.0Reference data
hydrogen peroxide+methanolformaldehyde+2water
Catalysed by MPO or PRDX6 or EPX or LPO
Reaction pageLeft to rightBalancedEC 1.11.1.7, 1.11.1.8, 1.11.2.2lysosome
Human-GEM MAR08752CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, lysosome
Human-GEM MAR08753CC BY 4.0Reference data
Reaction pageReversibleBalancedcytosol, endoplasmic reticulum
Human-GEM MAR08921CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09372CC BY 4.0Reference data
CHEBI:57927+watermethanol+oxaloacetate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:10564CC BY 4.0Reference data
CHEBI:16183+NADH(2-)+dioxygen+hydronmethanol+NAD(1-)+water
Reaction pageDirection not assertedBalanced
Rhea RHEA:13637CC BY 4.0Reference data
CHEBI:16183+NADPH(4-)+dioxygen+hydronmethanol+NADP(3-)+water
Reaction pageDirection not assertedBalanced
Rhea RHEA:13641CC BY 4.0Reference data
Other names
9 names
Resolves to: methanol
- Also called
- carbinolCH3OHMeOHMethyl alcoholMethylalkoholspirit of woodwood alcoholwood naphthawood spirit