Proteins/UNIPROT:Q8N7Z5

ANKRD31

ProteinUNIPROT:Q8N7Z5

Required for DNA double-strand breaks (DSBs) formation during meiotic recombination. Regulates the spatial and temporal patterns of pre-DSB recombinosome assembly and recombination activity by acting as a scaffold that anchors REC114 and other factors to specific genomic locations, thereby regulating DSB formation. Plays a key role in recombination in the pseudoautosomal regions of sex chromosomes..

Function from UniProtKB (Q8N7Z5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

GenCC submitters' classifications

1 row

inherited primary ovarian failure has a germline basis in ANKRD31DiseaseGenCC HGNC:26853|MONDO:0019852Inferred only

Statements

24 statements

24 statements · 2 reference databases · Subject: ANKRD31 · Sources: gene ontology, Hetionet

Order

AGGF1 covaries with ANKRD31ProteinHetionet hetionet:covaries:256006-55109Inferred only
ANKRD31 covaries with AKAP13ProteinHetionet hetionet:covaries:11214-256006Inferred only
ANKRD31 covaries with ASXL2ProteinHetionet hetionet:covaries:256006-55252Inferred only
CPLANE1 covaries with ANKRD31ProteinHetionet hetionet:covaries:256006-65250Inferred only
ANKRD31 covaries with GCNT4ProteinHetionet hetionet:covaries:256006-51301Inferred only
ANKRD31 covaries with HMCN1ProteinHetionet hetionet:covaries:256006-83872Inferred only
HSPA1A covaries with ANKRD31ProteinHetionet hetionet:covaries:256006-3304Inferred only
ANKRD31 covaries with IL4RProteinHetionet hetionet:covaries:256006-3566Inferred only
LUZP1 covaries with ANKRD31ProteinHetionet hetionet:covaries:256006-7798Inferred only
ANKRD31 covaries with NESProteinHetionet hetionet:covaries:10763-256006Inferred only
ANKRD31 covaries with NGRNProteinHetionet hetionet:covaries:256006-51335Inferred only
PCDHB15 covaries with ANKRD31ProteinHetionet hetionet:covaries:256006-56121Inferred only

Show the remaining 12

ANKRD31 covaries with PUS7LProteinHetionet hetionet:covaries:256006-83448Inferred only
ANKRD31 covaries with SCAF11ProteinHetionet hetionet:covaries:256006-9169Inferred only
SHOC1 covaries with ANKRD31ProteinHetionet hetionet:covaries:158401-256006Inferred only
ANKRD31 covaries with SMG7ProteinHetionet hetionet:covaries:256006-9887Inferred only
ANKRD31 covaries with TMEM254ProteinHetionet hetionet:covaries:256006-80195Inferred only
ANKRD31 covaries with TRMT5ProteinHetionet hetionet:covaries:256006-57570Inferred only
ANKRD31 covaries with ZBTB49ProteinHetionet hetionet:covaries:166793-256006Inferred only
ZDHHC4 covaries with ANKRD31ProteinHetionet hetionet:covaries:256006-55146Inferred only
ZMYM5 covaries with ANKRD31ProteinHetionet hetionet:covaries:256006-9205Inferred only
ANKRD31 covaries with ZNF235ProteinHetionet hetionet:covaries:256006-9310Inferred only
ANKRD31 covaries with ZNF629ProteinHetionet hetionet:covaries:23361-256006Inferred only
ANKRD31 regulates positive regulation of meiotic DNA double-strand break formationBiological processgene ontology Q8N7Z5|GO:1903343Inferred only

Other names

1 name

Resolves to: ANKRD31

Also called: Ankyrin repeat domain-containing protein 31

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