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Proteins/UNIPROT:O94782
Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity..
Function from UniProtKB (O94782), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
120 statements
120 statements · 4 reference databases · Subject: USP1 · Sources: gene ontology, Hetionet, Reactome, WikiPathways
1 reaction
5 names
Resolves to: USP1
Human-GEM MAR09490CC BY 4.0Reference data