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Proteins/UNIPROT:P48163
Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate..
Function from UniProtKB (P48163), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
120 statements
120 statements · 9 reference databases · Subject: ME1 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
3 reactions
(S)-malate+NADP(3-)carbon dioxide+NADPH(4-)+pyruvate
Reaction pageLeft to rightBalancedEC 1.1.1.38, 1.1.1.40cytosol
Human-GEM MAR04089CC BY 4.0Reference data
2 names
Resolves to: ME1
Reaction pageLeft to rightBalanced
Rhea RHEA:15641CC BY 4.0Reference data
(S)-malate+NADP(3-)pyruvate+carbon dioxide+NADPH(4-)
Reaction pageReversibleBalanced
Rhea RHEA:18253CC BY 4.0Reference data