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Proteins/UNIPROT:Q8NB91

FANCB

Protein·UNIPROT:Q8NB91

Open in the graph

DNA repair protein required for FANCD2 ubiquitination..

Function from UniProtKB (Q8NB91), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

4 rows

Fanconi anemia has a germline basis in FANCBDiseaseGenCC HGNC:3583|MONDO:0019391Inferred only
Fanconi anemia complementation group B has a germline basis in FANCBDiseaseGenCC HGNC:3583|MONDO:0010351Inferred only
VACTERL association, X-linked, with or without hydrocephalus has a germline basis in FANCBDiseaseGenCC HGNC:3583|MONDO:0010752Inferred only
VACTERL with hydrocephalus has a germline basis in FANCBDiseaseGenCC HGNC:3583|MONDO:0010172Inferred only

Statements

23 statements

23 statements · 4 reference databases · Subject: FANCB · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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FANCB covaries with ACDProteinHetionet hetionet:covaries:2187-65057Inferred only
BEX5 covaries with FANCBProteinHetionet hetionet:covaries:2187-340542Inferred only
CT83 covaries with FANCBProteinHetionet hetionet:covaries:203413-2187Inferred only
FANCB covaries with LRRC31ProteinHetionet hetionet:covaries:2187-79782Inferred only
FANCB covaries with MYL5ProteinHetionet hetionet:covaries:2187-4636Inferred only
PAGE4 covaries with FANCBProteinHetionet hetionet:covaries:2187-9506Inferred only
FANCB covaries with PLEKHG1ProteinHetionet hetionet:covaries:2187-57480Inferred only
FANCB covaries with ZNF581ProteinHetionet hetionet:covaries:2187-51545Inferred only
F3 interacts with FANCBProteinHetionet hetionet:interacts:2152-2187Inferred only
FANCB interacts with FAAP100ProteinHetionet hetionet:interacts:2187-80233Inferred only
FANCB interacts with FANCLProteinHetionet hetionet:interacts:2187-55120Inferred only
FANCB interacts with UBCProteinHetionet hetionet:interacts:2187-7316Inferred only

Show the remaining 11

FANCB participates in Antimicrobial mechanism of IFN-stimulated genesPathwayReactome R-HSA-1169410Inferred only
FANCB participates in Cytokine Signaling in Immune systemPathwayReactome R-HSA-1280215Inferred only
FANCB participates in DNA RepairPathwayReactome R-HSA-73894Inferred only
FANCB participates in Fanconi anemiaPathwayWikiPathways WP5465Inferred only
FANCB participates in Fanconi Anemia PathwayPathwayReactome R-HSA-6783310Inferred only
FANCB participates in Genes and complexes involved in the DNA repair pathwaysPathwayWikiPathways WP4946Inferred only
FANCB participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
FANCB participates in Interferon SignalingPathwayReactome R-HSA-913531Inferred only
FANCB participates in PKR-mediated signalingPathwayReactome R-HSA-9833482Inferred only
FANCB regulates negative regulation of double-strand break repair via homologous recombinationBiological processgene ontology Q8NB91|GO:2000042Inferred only
FANCB regulates positive regulation of double-strand break repair via homologous recombinationBiological processgene ontology Q8NB91|GO:1905168Inferred only

Other names

4 names

Resolves to: FANCB

Also called: FAAP95FACBFanconi anemia-associated polypeptide of 95 kDaProtein FACB

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