(11Z,14Z)-eicosadienoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

656 compounds within 3 steps: 4 in 1, 144 in 2, 508 in 3

Three steps

a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by LPCAT2, LPCAT1cytosolOne of 2 routes
a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by LPCAT4cytosol
1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-O-(1Z)-alkenyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by FADS2, FADS1, LPCAT4, LPCAT3
1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octanoyl-CoA = 1-O-(1Z)-alkenyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by BAAT, ACOT6, ACOT1, CROT and 1 morecytosol, mitochondrial matrix
1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-O-(1Z)-alkenyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 7 morecytosol
tetracosan-1-olReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. tetracosanoyl-CoA + 2 NADPH + 2 H(+) = tetracosan-1-ol + 2 NADP(+) + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
(2E,9Z)-hexadecadienoyl-CoAReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. medium-chain acyl-CoA dehydrogenase (palmitoleoyl-CoA)
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 3 routes
trans-2-heptadecenoyl-CoAReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (margaric acid)
3. medium-chain acyl-CoA dehydrogenase (heptadecanoyl-CoA)
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 2 routes
(2E,9Z)-octadecadienoyl-CoAReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. Transport of octadecenoyl-CoA into Mitochondrial Matrix
3. medium-chain acyl-CoA dehydrogenase (oleoyl-CoA)
Catalysed by BAAT, ACOT6, ACOT1, CPT1A and 6 morecytosol, mitochondrial matrixOne of 2 routes
(2E,9Z,12Z)-octadecatrienoyl-CoAReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. (9Z,12Z)-octadecadienoyl-CoA + oxidized [electron-transfer flavoprotein] + H(+) = (2E,9Z,12Z)-octadecatrienoyl-CoA + reduced [electron-transfer flavoprotein]
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 10 morecytosol
(2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoAReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + O2 = (2E,4Z,7Z,10Z,13Z,16Z,19Z)-docosaheptaenoyl-CoA + H2O2
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
N-(9Z-octadecenoyl)-sphing-4-enineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. acyl-CoA:sphingosine N-acyltransferase
3. N-(9Z-octadecenoyl)-sphing-4-enine + H2O = sphing-4-enine + (9Z)-octadecenoate
Catalysed by BAAT, ACOT6, ACOT1, ASAH1 and 4 morecytosol, Golgi apparatus
(5Z,8Z,11Z)-eicosatrienoateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by BAAT, ACOT6, ACOT1cytosol, extracellular spaceOne of 12 routes
9-cis-retinolReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. Palmitoyl-CoA:retinol O-acyltransferase
3. 11-cis-retinol = 9-cis-retinol
Catalysed by BAAT, ACOT6, ACOT1, DGAT1 and 5 morecytosol
N-hexadecanoyl-sphinganine-1-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-sphinganine-1-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by LPGAT1, SGMS1, SGMS2cytosol
N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = N-hexadecanoyl-(4R)-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by LPGAT1, SGMS1, SGMS2cytosol
an N-acyl-(4R)-4-hydroxysphinganine-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphocholine = an N-acyl-(4R)-4-hydroxysphinganine-phosphocholine + a 1,2-diacyl-sn-glycerol
Catalysed by LPGAT1, SGMS1, SGMS2cytosol
N-hexadecanoyl-sphinganine-1-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. N-hexadecanoylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-sphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
an N-acylsphinganine-1-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. sphingosine N-acyltransferase (sphinganine)
3. an N-acylsphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acylsphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by CERS1, CERS6, CERS3, CERS5 and 4 morecytosolOne of 2 routes
N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. N-hexadecanoyl-(4R)-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = N-hexadecanoyl-(4R)-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 1-acyl-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CoA
3. an N-acyl-(4R)-4-hydroxysphinganine + a 1,2-diacyl-sn-glycero-3-phosphoethanolamine = an N-acyl-(4R)-4-hydroxysphinganine-1-phosphoethanolamine + a 1,2-diacyl-sn-glycerol
Catalysed by LPCAT4, LPCAT3, MBOAT1, MBOAT2 and 2 morecytosol
1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositolReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-(9Z-octadecenoyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-1D-myo-inositol + CoA
Catalysed by FADS2, FADS1, AGPAT3, AGPAT5
1-heptadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-heptadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphate + CoA
Catalysed by FADS2, FADS1, AGPAT3
tricosanoateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. (10Z)-heptadecenoic acid formation
3. (10Z)-heptadecenoic acid formation
Catalysed by BAAT, ACOT6, ACOT1cytosol, extracellular spaceOne of 13 routes
thio-Mo-molybdopterinReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. N-acetylglutamate synthase (N-acetyl-L-cysteine)
3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by BAAT, ACOT6, ACOT1, NAGS and 1 morecytosol, mitochondrial matrix
cholesteryl octadecanoateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol, endoplasmic reticulumOne of 6 routes
cholesteryl (5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + cholesterol = cholesteryl (5Z,8Z,11Z,14Z)-eicosatetraenoate + CoA
Catalysed by FADS2, FADS1, SOAT2, SOAT1
N-octadecanoylhexadecasphinganineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. hexadecasphinganine + octadecanoyl-CoA = N-octadecanoylhexadecasphinganine + CoA + H(+)
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-eicosanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
glycodeoxycholateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. cholate-CoA ligase (3alpha,12alpha-dihydroxy-5beta-cholanate)
3. deoxycholoyl-CoA to glycodeoxycholate conversion
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 1 morecytosolOne of 3 routes
sphinga-4E,14Z-dienineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. acyl-CoA:sphingosine N-acyltransferase
3. sphing-4-enine + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = sphinga-4E,14Z-dienine + 2 Fe(III)-[cytochrome b5] + 2 H2O
Catalysed by BAAT, ACOT6, ACOT1, ASAH1 and 4 morecytosol, Golgi apparatus
1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerolReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1'-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-3'-[1-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1',3'-bis-[1,2-di-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + octadecanoyl-CoA = a 1-acyl-2-octadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 7 morecytosol
cholesteryl (9Z)-hexadecenoateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. (9Z)-hexadecenoyl-CoA + cholesterol = cholesteryl (9Z)-hexadecenoate + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
(9Z,12Z,15Z-octadecatrienoyl)-cholesterolReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (linolenate)
3. (9Z,12Z,15Z)-octadecatrienoyl-CoA + cholesterol = (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
a monoacyl-sn-glycero-3-phosphocholineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a monoacyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)
Catalysed by LPGAT1, PNLIPRP2cytosol
2-(acylamino)ethyl fatty acidReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. an N-acylethanolamine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 2-(acylamino)ethyl fatty acid + a 2-acyl-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, PLA2G15cytosolOne of 2 routes
1-O-acyl-N-(acetyl)-sphing-4-enineReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by LPGAT1, PLA2G15cytosolOne of 8 routes
O-tetradecanoyl-(R)-carnitineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + (R)-carnitine = O-tetradecanoyl-(R)-carnitine + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
O-octadecanoyl-(R)-carnitineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. (R)-carnitine + octadecanoyl-CoA = O-octadecanoyl-(R)-carnitine + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 7 morecytosol
O-eicosanoyl-(R)-carnitineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + (R)-carnitine = O-eicosanoyl-(R)-carnitine + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosol
O-4,8-dimethylnonanoyl-(R)-carnitineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. Carnitine O-Palmitoyltransferase
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by BAAT, ACOT6, ACOT1, CPT1A and 4 morecytosol, peroxisomeOne of 7 routes
1,2-diacyl-sn-glycero-3-phosphoethanolReach from here →
1. acyl-CoA pool formation and breakdown
2. a 2-acyl-sn-glycero-3-phosphocholine + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphocholine + CoA
3. ethanol + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1,2-diacyl-sn-glycero-3-phosphoethanol + choline
Catalysed by LPGAT1, PLD1cytosol
1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 7 morecytosol
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 7 morecytosol
(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterolReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (EPA)
3. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 9 morecytosol, endoplasmic reticulumOne of 6 routes
1-O-(9Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
2. (8Z,11Z,14Z)-eicosatrienoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-O-(9Z-octadecenyl)-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-O-(9Z-octadecenyl)-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by FADS2, FADS1, AGPAT3
N-tetradecanoylglycineReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 8 morecytosolOne of 2 routes
N-eicosanoylglycinateReach from here →
1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 7 morecytosolOne of 2 routes