(2E)-octadecenoyl-CoA

362,296 routes · scope human · up to 3 steps · built 6 October 2026 · Reactions · API

673 compounds within 3 steps: 3 in 1, 166 in 2, 504 in 3

Three steps

(9Z,12Z,15Z-octadecatrienoyl)-cholesterolReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (linolenate)
3. (9Z,12Z,15Z)-octadecatrienoyl-CoA + cholesterol = (9Z,12Z,15Z-octadecatrienoyl)-cholesterol + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
cholesteryl (8Z,11Z,14Z)-eicosatrienoateReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
3. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol, endoplasmic reticulum
1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoserineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)
3. 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoserine + H2O = 1-octadecanoyl-sn-glycero-3-phosphoserine + (9Z,12Z)-octadecadienoate + H(+)
Catalysed by FADS2, ACOT8, ACOT2, THEM5 and 2 morecytosol
O-tetradecanoyl-(R)-carnitineReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + (R)-carnitine = O-tetradecanoyl-(R)-carnitine + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
O-eicosanoyl-(R)-carnitineReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + (R)-carnitine = O-eicosanoyl-(R)-carnitine + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosol
O-(9Z)-octadecenoyl-(R)-carnitineReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. (R)-carnitine + (9Z)-octadecenoyl-CoA = O-(9Z)-octadecenoyl-(R)-carnitine + CoA
Catalysed by TECRL, TECR, SCD, SCD5 and 1 morecytosol
O-4,8-dimethylnonanoyl-(R)-carnitineReach from here →
1. Carnitine O-Palmitoyltransferase
2. Carnitine O-Palmitoyltransferase
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by CPT1A, CPT1C, CPT1B, CRAT and 1 morecytosol, peroxisomeOne of 7 routes
beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enineReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. sphing-4-enine + octadecanoyl-CoA = N-octadecanoylsphing-4-enine + CoA + H(+)
3. beta-D-glucosyl-(1<->1)-N-octadecanoylsphing-4-enine + cholesterol = cholesteryl 3-beta-D-glucoside + N-octadecanoylsphing-4-enine
Catalysed by TECRL, TECR, CERS1, TLCD3B and 3 morecytosol
(5Z,8Z,11Z,14Z,17Z-eicosapentaenoyl)-cholesterolReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (EPA)
3. Acyl-CoA:cholesterol O-acyltransferase
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 9 morecytosol, endoplasmic reticulumOne of 2 routes
1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphateReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
3. 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CTP + H(+) = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-cytidine-5'-diphosphate + diphosphate
Catalysed by FADS2, AGPAT4, CDS2, CDS1cytosol
1-decanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. octadecanoyl-CoA:NADP+ trans-2-oxidoreductase
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-decanoylglycerol + (9Z)-octadecenoyl-CoA = 1-decanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by TECRL, TECR, SCD, SCD5 and 1 morecytosol
N-tetradecanoylglycineReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + glycine = N-tetradecanoylglycine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosolOne of 2 routes
N-eicosanoylglycinateReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + glycine = N-eicosanoylglycinate + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosolOne of 2 routes
N-docosanoylglycineReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (behenic acid)
3. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosolOne of 2 routes
N-hexacosanoylglycineReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (cerotic acid)
3. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 8 morecytosolOne of 2 routes
an N(2)-acyl-L-glutamineReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by FADS2, GLYATL1B, GLYATL1cytosol
(2E,5Z)-tetradecadienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (physeteric acid)
3. medium-chain acyl-CoA dehydrogenase (5-tetradecenoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 4 routes
(2E,7Z)-hexadecadienoyl-CoAReach from here →
1. Carnitine O-Palmitoyltransferase
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
3. medium-chain acyl-CoA dehydrogenase (7-hexadecenoyl-CoA)
Catalysed by CPT1A, CPT1C, CPT1B, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 4 routes
cholesteryl (11Z)-octadecenoateReach from here →
1. Carnitine O-Palmitoyltransferase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
3. (11Z)-octadecenoyl-CoA + cholesterol = cholesteryl (11Z)-octadecenoate + CoA
Catalysed by CPT1A, CPT1C, CPT1B, SOAT1cytosol
a 3-oxoacyl-CoAReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. acyl-CoA pool formation and breakdown
3. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
Catalysed by FADS2, ACAA1, SCP2, ACAA2 and 1 morecytosol
13-hydroperoxy-(9Z,11E)-octadecadienoateReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)
3. (9Z,12Z)-octadecadienoate + O2 = 13-hydroperoxy-(9Z,11E)-octadecadienoate
Catalysed by FADS2, ACOT8, ACOT2, THEM5 and 2 morecytosol
(13S)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. fatty acyl-CoA desaturase (N-C18:1CoA -> N-C18:2CoA)
2. (9Z,12Z)-octadecadienoyl-CoA + H2O = (9Z,12Z)-octadecadienoate + CoA + H(+)
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (13S)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O
Catalysed by FADS2, ACOT8, ACOT2, THEM5 and 3 morecytosol
taurochenodeoxycholateReach from here →
1. Carnitine O-Palmitoyltransferase
2. Propanoyl-CoA:acetyl-CoA C-acyltransferase
3. 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:taurine N-choloyltransferase
Catalysed by CPT1A, CPT1C, CPT1B, ACAA1 and 3 morecytosol, peroxisomeOne of 5 routes