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A reference for what the literature reports. Not medical advice.

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cysteamine

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

25 compounds within 3 steps: 3 in 1, 5 in 2, 17 in 3

Does it reach a compound?

One step

CHEBI:16668Reach from here →
1. Cysteamine:oxygen oxidoreductase
Catalysed by ADOcytosolOne of 2 routes
(R)-pantetheineReach from here →
1. (R)-pantetheine amidohydrolase
Catalysed by VNN1, VNN2cytosol
hypotaurineReach from here →
1. cysteamine + O2 = hypotaurine + H(+)
Catalysed by ADO

Two steps

pantetheine 4'-phosphateReach from here →
1. (R)-pantetheine amidohydrolase
2. ATP:pantothenate 4'-phosphotransferase
Catalysed by VNN1, VNN2, PANK1, PANK2 and 1 morecytosolOne of 2 routes
(R)-pantothenateReach from here →
1. (R)-pantetheine amidohydrolase
2. (R)-pantetheine + H2O = cysteamine + (R)-pantothenate
Catalysed by VNN1, VNN2cytosol
taurine

Three steps

(R)-4'-phosphopantothenateReach from here →
Catalysed by VNN1, VNN2, PANK2cytosol, mitochondrial matrixOne of 3 routes
CHEBI:1146900Reach from here →
Catalysed by ADO

Reach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular

Catalysed by ADOcytosol, extracellular spaceOne of 4 routes

3-sulfino-L-alanineReach from here →

cysteamine + O2 = hypotaurine + H(+)
3-sulfino-L-alanine + H(+) = hypotaurine + CO2

Catalysed by ADO, GADL1, CSAD

pantothenic acidReach from here →

(R)-pantetheine amidohydrolase
(R)-pantetheine amidohydrolase

Catalysed by VNN1, VNN2cytosolOne of 2 routes

cytosol, extracellular space, peroxisome

One of 15 routes

tauroursodeoxycholateReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
taurine to tauroursodeoxycholate conversion

Catalysed by ADOcytosol, extracellular spaceOne of 2 routes

3-sulfinopyruvateReach from here →

cysteamine + O2 = hypotaurine + H(+)
3-sulfino-L-alanine + H(+) = hypotaurine + CO2
3-sulfino-L-alanine:2-oxoglutarate aminotransferase

Catalysed by ADO, GADL1, CSAD, GOT1cytosolOne of 2 routes

taurolithocholateReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
bile acid-CoA:amino acid N-acyltransferase (lithocholate)

Catalysed by ADO, BAATcytosol, extracellular spaceOne of 2 routes

AH2Reach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)

Catalysed by ADO, MTO1cytosol, extracellular space

chlorine(.)Reach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
Neurotransmitter:Sodium Symporter (Nss) Tcdb:2.A.22.3.3

Catalysed by ADO, SLC6A6cytosol, extracellular spaceOne of 2 routes

L-aspartateReach from here →

cysteamine + O2 = hypotaurine + H(+)
3-sulfino-L-alanine + H(+) = hypotaurine + CO2
transport of 3-sulfinoalanine and aspartate (cytosol to mitochondria)

Catalysed by ADO, GADL1, CSAD, SLC25A12 and 1 moremitochondrial matrix, cytosolOne of 4 routes

taurocholateReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
Choloyl-CoA:glycine N-choloyltransferase

Catalysed by ADO, BAATcytosol, extracellular space, peroxisomeOne of 3 routes

taurodeoxycholateReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
bile acid-CoA:amino acid N-acyltransferase (taurodeoxycholate)

Catalysed by ADO, BAATcytosol, extracellular spaceOne of 2 routes

L-ornithineReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
taurine + L-arginine = taurocyamine + L-ornithine

Catalysed by ADO, GATMcytosol, extracellular space

3'-dephospho-CoAReach from here →

(R)-pantetheine amidohydrolase
ATP:pantothenate 4'-phosphotransferase
ATP:pantetheine-4'-phosphate adenylyltransferase

Catalysed by VNN1, VNN2, PANK1, PANK2 and 2 morecytosolOne of 2 routes

7,8-dihydrofolateReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)

Catalysed by ADO, MTO1cytosol, extracellular space

taurocyamineReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
taurine + L-arginine = taurocyamine + L-ornithine

Catalysed by ADO, GATMcytosol, extracellular space

L-cysteateReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
L-cysteate + H(+) = taurine + CO2

Catalysed by ADO, GADL1, CSADcytosol, extracellular space

N-[(R)-4-phosphopantothenoyl]-L-cysteineReach from here →

(R)-pantetheine amidohydrolase
ATP:pantothenate 4'-phosphotransferase
N-[(R)-4'-Phosphopantothenoyl]-L-cysteine carboxy-lyase

Catalysed by VNN1, VNN2, PANK1, PANK2 and 2 morecytosol

taurochenodeoxycholateReach from here →

Cysteamine:oxygen oxidoreductase
Hypotaurine Oxidase, Extracellular
3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:taurine N-choloyltransferase

Catalysed by ADO, BAATcytosol, extracellular space, peroxisomeOne of 3 routes