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(R)-4'-phosphopantothenate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

6 compounds within 3 steps: 2 in 1, 2 in 2, 2 in 3

Does it reach a compound?

One step

(R)-pantothenateReach from here →
1. (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)
Catalysed by PANK1, PANK2, PANK3
N-[(R)-4-phosphopantothenoyl]-L-cysteineReach from here →
1. (R)-4'-phosphopantothenate:L-cysteine ligase
Catalysed by PPCScytosolOne of 4 routes

Two steps

pantetheine 4'-phosphateReach from here →
1. (R)-4'-phosphopantothenate:L-cysteine ligase
2. N-[(R)-4'-Phosphopantothenoyl]-L-cysteine carboxy-lyase
Catalysed by PPCS, PPCDCcytosolOne of 2 routes
(R)-4'-phosphopantetheineReach from here →
1. (R)-4'-phosphopantothenate:L-cysteine ligase
2. N-[(R)-4-phosphopantothenoyl]-L-cysteine + H(+) = (R)-4'-phosphopantetheine + CO2
Catalysed by PPCS, PPCDCcytosol

Three steps

(R)-pantetheineReach from here →
Catalysed by PPCS, PPCDC, PANK4cytosolOne of 3 routes
3'-dephospho-CoAReach from here →
Catalysed by PPCS

cytosol

One of 3 routes