Compound
pantothenic acid
A member of the class of pantothenic acids that is an amide formed from pantoic acid and β-alanine.
Definition from ChEBI (CHEBI:7916), read 2026-09-23. CC BY 4.0.
What it touches on the way
Mechanistic reach
6 entities
6 entities reached.
0 reported hops6 assembled from the scaffold
- SLC5A6ProteinUNIPROT:Q9Y289transported byInferred only16 paths4 endpoints
- PANK2ProteinUNIPROT:Q9BZ23substrate ofInferred only14 paths7 endpoints
- VNN1ProteinUNIPROT:O95497substrate ofInferred only10 paths10 endpoints
- VNN2ProteinUNIPROT:O95498substrate ofInferred only7 paths7 endpoints
- PANK1ProteinUNIPROT:Q8TE04substrate ofInferred only5 paths5 endpoints
- PANK3ProteinUNIPROT:Q9H999substrate ofInferred only5 paths5 endpoints
What the reference databases state
Statements
12 statements
12 statements · 1 reference database · Subject: pantothenic acid · Sources: Human-GEM
- pantothenic acid is converted to (R)-4'-phosphopantothenateCompoundHuman-GEM MAR01634Inferred only
- pantothenic acid is converted to (R)-4'-phosphopantothenateCompoundHuman-GEM MAR04718Inferred only
- pantothenic acid is a substrate of PANK1ProteinHuman-GEM MAR04718Inferred only
- pantothenic acid is a substrate of PANK2ProteinHuman-GEM MAR01634Inferred only
- pantothenic acid is a substrate of PANK2ProteinHuman-GEM MAR04718Inferred only
- pantothenic acid is a substrate of PANK3ProteinHuman-GEM MAR04718Inferred only
- pantothenic acid is a substrate of VNN1ProteinHuman-GEM MAR04717Inferred only
- pantothenic acid is a substrate of VNN2ProteinHuman-GEM MAR04717Inferred only
- pantothenic acid is transported by SLC5A6ProteinHuman-GEM MAR09607Inferred only
- pantothenic acid is transported by SLC5A6ProteinHuman-GEM MAR01636Inferred only
- pantothenic acid is transported by SLC5A6ProteinHuman-GEM MAR08930Inferred only
- pantothenic acid is transported by SLC5A6ProteinHuman-GEM MAR04721Inferred only
Reactions
10 reactions
ATP+pantothenic acidADP+(R)-4'-phosphopantothenate+proton
Catalysed by PANK2
Reaction pageLeft to rightBalancedEC 2.7.1.33GO:0005759
Human-GEM MAR01634CC BY 4.0Reference data
ATP+water+sodium(1+)+pantothenic acidADP+proton+sodium(1+)+pantothenic acid+phosphate(3-)
Transported by SLC5A6
Reaction pageLeft to rightBalancedGO:0005829, GO:0005615
Human-GEM MAR01636CC BY 4.0Reference data
water+(R)-pantetheinecysteamine+pantothenic acid
Reaction pageReversibleBalancedEC 3.5.1.92GO:0005829
Human-GEM MAR04717CC BY 4.0Reference data
ATP+pantothenic acidADP+(R)-4'-phosphopantothenate+proton
Catalysed by PANK3 or PANK2 or PANK1
Reaction pageLeft to rightBalancedEC 2.7.1.33GO:0005829
Human-GEM MAR04718CC BY 4.0Reference data
sodium(1+)+pantothenic acidsodium(1+)+pantothenic acid
Transported by SLC5A6
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR04721CC BY 4.0Reference data
ATP+water+2sodium(1+)+pantothenic acidADP+proton+2sodium(1+)+pantothenic acid+phosphate(3-)
Transported by SLC5A6
Reaction pageLeft to rightBalancedGO:0005829, GO:0005615
Human-GEM MAR08930CC BY 4.0Reference data
water+(R)-pantetheinecysteamine+pantothenic acid
Reaction pageLeft to rightBalancedGO:0005615
Human-GEM MAR08986CC BY 4.0Reference data
pantothenic acidpantothenic acid
Reaction pageReversibleBalancedGO:0005615, GO:0005829
Human-GEM MAR09057CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR09145CC BY 4.0Reference data
2sodium(1+)+pantothenic acid2sodium(1+)+pantothenic acid
Transported by SLC5A6
Reaction pageLeft to rightBalancedGO:0005615, GO:0005829
Human-GEM MAR09607CC BY 4.0Reference data
Where it reaches
2 systems, 2 regions, 3 tissues, 3 transporter routes — routes, not measurements: transporters known to carry pantothenic acid are expressed there, and no source reports it arriving.
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Other names
3 names
Resolves to: pantothenic acid
- Also called
- N-(2,4-dihydroxy-3,3-dimethylbutanoyl)-beta-alanineN-(2,4-dihydroxy-3,3-dimethylbutanoyl)-β-alanine
- Systematic name
- 3-(2,4-dihydroxy-3,3-dimethylbutanamido)propanoic acid