Compound
(R)-pantetheine
An intermediate in the pathway of coenzyme A formation in mammalian liver and some microorganisms.
Structure
Loading the model…
- Class
- Organic compound
- Formula
- C11H22N2O4S
- Mass
- 278.374 g/mol
- Charge
- 0
- InChIKey
- ZNXZGRMVNNHPCA-VIFPVBQESA-N
- SMILES
- CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)NCCS
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
5 entities
5 entities reached.
0 reported hops5 assembled from the scaffold
- VNN1ProteinUNIPROT:O95497substrate ofInferred only20 paths10 endpoints
- PANK2ProteinUNIPROT:Q9BZ23substrate ofInferred only14 paths7 endpoints
- VNN2ProteinUNIPROT:O95498substrate ofInferred only14 paths7 endpoints
- PANK1ProteinUNIPROT:Q8TE04substrate ofInferred only10 paths5 endpoints
- PANK3ProteinUNIPROT:Q9H999substrate ofInferred only10 paths5 endpoints
What the reference databases state
Statements
17 statements
17 statements · 2 reference databases · Subject: (R)-pantetheine · Sources: Human-GEM, Rhea
- (R)-4'-phosphopantetheine is converted to (R)-pantetheineCompoundRhea RHEA:68328Inferred only
- (R)-4'-phosphopantetheine is converted to (R)-pantetheineCompoundRhea RHEA:22472Inferred only
- (R)-pantetheine is converted to (R)-4'-phosphopantetheineCompoundRhea RHEA:22472Inferred only
- (R)-pantetheine is converted to pantetheine 4'-phosphateCompoundHuman-GEM MAR04715Inferred only
- pantetheine 4'-phosphate is converted to (R)-pantetheineCompoundHuman-GEM MAR08792Inferred only
- pantetheine 4'-phosphate is converted to (R)-pantetheineCompoundHuman-GEM MAR08984Inferred only
- (R)-pantetheine is converted to pantetheine 4'-phosphateCompoundHuman-GEM MAR04714Inferred only
- (R)-pantetheine is a substrate of PANK1ProteinHuman-GEM MAR04715Inferred only
- (R)-pantetheine is a substrate of PANK1ProteinHuman-GEM MAR04714Inferred only
- (R)-pantetheine is a substrate of PANK2ProteinHuman-GEM MAR04714Inferred only
- (R)-pantetheine is a substrate of PANK2ProteinHuman-GEM MAR04715Inferred only
- (R)-pantetheine is a substrate of PANK3ProteinHuman-GEM MAR04714Inferred only
Show the remaining 5
- (R)-pantetheine is a substrate of PANK3ProteinHuman-GEM MAR04715Inferred only
- (R)-pantetheine is a substrate of VNN1ProteinHuman-GEM MAR04717Inferred only
- (R)-pantetheine is a substrate of VNN1ProteinRhea RHEA:13445Inferred only
- (R)-pantetheine is a substrate of VNN2ProteinHuman-GEM MAR04717Inferred only
- (R)-pantetheine is a substrate of VNN2ProteinRhea RHEA:13445Inferred only
Reactions
14 reactions
ATP+(R)-pantetheineADP+proton+pantetheine 4'-phosphate
Catalysed by PANK3 or PANK2 or PANK1
Reaction pageLeft to rightBalancedEC 2.7.1.33, 2.7.1.34cytosol
Human-GEM MAR04714CC BY 4.0Reference data
ATP+(R)-pantetheineADP+proton+pantetheine 4'-phosphate
Catalysed by PANK3 or PANK2 or PANK1
Reaction pageLeft to rightBalancedEC 2.7.1.33, 2.7.1.34mitochondrial matrix
Human-GEM MAR04715CC BY 4.0Reference data
proton+MAM02623ccarbon dioxide+(R)-pantetheine
Reaction pageLeft to rightBalancedEC 4.1.1.30cytosol
Human-GEM MAR04716CC BY 4.0Reference data
water+(R)-pantetheinecysteamine+pantothenic acid
Reaction pageReversibleBalancedEC 3.5.1.92cytosol
Human-GEM MAR04717CC BY 4.0Reference data
(R)-pantetheine(R)-pantetheine
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR04720CC BY 4.0Reference data
water+pantetheine 4'-phosphate(R)-pantetheine+phosphate(3-)
Catalysed by PANK4
Reaction pageLeft to rightBalancedEC 3.1.3.110cytosol
Human-GEM MAR08792CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR08965CC BY 4.0Reference data
water+pantetheine 4'-phosphate(R)-pantetheine+phosphate(3-)
Reaction pageLeft to rightBalancedextracellular space
Human-GEM MAR08984CC BY 4.0Reference data
water+(R)-pantetheinecysteamine+pantothenic acid
Reaction pageLeft to rightBalancedextracellular space
Human-GEM MAR08986CC BY 4.0Reference data
(R)-pantetheine+watercysteamine+(R)-pantothenate
Reaction pageLeft to rightBalanced
Rhea RHEA:13445CC BY 4.0Reference data
CHEBI:58480+hydron(R)-pantetheine+carbon dioxide
Reaction pageDirection not assertedBalanced
Rhea RHEA:15077CC BY 4.0Reference data
(R)-pantetheine+ATP(4-)(R)-4'-phosphopantetheine+ADP(3-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:22472CC BY 4.0Reference data
On the label
Labelled products
2 products
Source: NIH DSLD · Ingredient: (R)-pantetheine · 2 products · Declared amount per serving: 50–50 mg (2 products)
2 labels state an amount0 do not
- Viva VitaminsCholesterol Caps50 mgper 1 Capsule(s)DSLD:1783
- Viva VitaminsCholesterol Caps50 mgper 1 Capsule(s)DSLD:237119
Label record: NIH Office of Dietary Supplements · CC0
Other names
4 names
Resolves to: (R)-pantetheine
- Also called
- D-PantetheineLactobacillus bulgaricus factorPantetheine
- Systematic name
- (2R)-2,4-dihydroxy-3,3-dimethyl-N-{3-oxo-3-[(2-sulfanylethyl)amino]propyl}butanamide