N-acetyl-D-glucosamine 6-phosphate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

254 compounds within 3 steps: 5 in 1, 26 in 2, 223 in 3

Three steps

(13Z)-docosenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 4 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes
nonadecanoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by CEMP1, AMDHD2, GNPNAT1, CPT1A and 2 morecytosolOne of 3 routes
1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosolOne of 8 routes
2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosolOne of 2 routes
1-octadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosolOne of 5 routes
2-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z)-octadecenoyl-2-octadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-octadecanoyl-sn-glycero-3-phosphocholine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
1-hexadecanoyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosolOne of 9 routes
2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine + 2-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-hexadecanoyl-N-(acetyl)-sphing-4-enine + 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosolOne of 2 routes
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosolOne of 3 routes
2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(9Z,12Z-octadecadienoyl)-N-acetylsphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosolOne of 3 routes
1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + N-(acetyl)-sphing-4-enine = 1-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-N-(acetyl)-sphing-4-enine + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + N-(acetyl)-sphing-4-enine = 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphoethanolamine + 1-hexadecanoyl-N-(acetyl)-sphing-4-enine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
16alpha,17alpha-dihydroxyprogesteroneReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. cytochrome P450 (17alpha-hydroxyprogesterone)
3. 17alpha-hydroxyprogesterone + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha,17alpha-dihydroxyprogesterone + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by CEMP1, AMDHD2, CYP17A1cytosol, endoplasmic reticulum
dodecanedioyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Activation of dodecanedioic acid
Catalysed by CEMP1, AMDHD2, GNPNAT1cytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Production of Sebacoylcarnitine
Catalysed by CEMP1, AMDHD2, GNPNAT1, CPT1A and 2 morecytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Production of Suberylcarnitine
Catalysed by CEMP1, AMDHD2, GNPNAT1, CPT1A and 2 morecytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by CEMP1, AMDHD2, GNPNAT1cytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes
2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. a 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + N-(acetyl)-sphing-4-enine = 2-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + 1-O-acyl-N-(acetyl)-sphing-4-enine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by CEMP1, AMDHD2, GNPNAT1, CPT1A and 2 morecytosol
(13Z)-eicosenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by CEMP1, AMDHD2, GNPNAT1, CRAT and 1 morecytosol, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by CEMP1, AMDHD2, GNPNAT1, ACAA1 and 3 morecytosol, peroxisome
hexadecanedioyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Production of Hexadecanedioylcarnitine
Catalysed by CEMP1, AMDHD2, GNPNAT1, CPT1A and 2 morecytosolOne of 2 routes
pristanoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. fatty-acid-CoA ligase
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2cytosolOne of 2 routes
2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-N-(acetyl)-sphing-4-enine + 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
undecanoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, ACSM4 and 5 morecytosolOne of 3 routes
1-octadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + N-(acetyl)-sphing-4-enine = 1-octadecanoyl-sn-glycero-3-phosphoserine + 1-(9Z-octadecenoyl)-N-(acetyl)-sphing-4-enine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosol
1-O-acyl-N-(acetyl)-sphing-4-enineReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + a 1,2-diacyl-sn-glycero-3-phosphocholine = 1-O-acyl-N-(acetyl)-sphing-4-enine + a 1-acyl-sn-glycero-3-phosphocholine
Catalysed by CEMP1, AMDHD2, ASAH1, PLA2G15cytosolOne of 8 routes
(5Z)-tetradecenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by CEMP1, AMDHD2, GNPNAT1, SLC27A2 and 7 morecytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. acetyl-CoA:D-glucosamine-6-phosphate N-acetyltransferase
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by CEMP1, AMDHD2, GNPNAT1, ACADM and 3 morecytosol, mitochondrial matrix
N-(acetyl)-sphing-4-enine-1-phosphateReach from here →
1. N-Acetyl-D-glucosamine-6-phosphate amidohydrolase
2. N-(acetyl)-sphing-4-enine + H2O = sphing-4-enine + acetate
3. N-(acetyl)-sphing-4-enine + ATP = N-(acetyl)-sphing-4-enine-1-phosphate + ADP + H(+)
Catalysed by CEMP1, AMDHD2, ASAH1, CERKcytosol