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Proteins/UNIPROT:Q06136
Catalyzes the reduction of 3'-oxosphinganine (3-ketodihydrosphingosine/KDS) to sphinganine (dihydrosphingosine/DHS), the second step of de novo sphingolipid biosynthesis..
Function from UniProtKB (Q06136), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
22 statements
22 statements · 6 reference databases · Subject: KDSR · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
2 reactions
3-oxosphinganine+proton+NADPH(4-)NADP(3-)+CHEBI:16566
Catalysed by KDSR
Reaction pageLeft to rightBalancedEC 1.1.1.102cytosol
Human-GEM MAR00741CC BY 4.0Reference data
sphinganine+NADP(3-)3-oxosphinganine+NADPH(4-)+hydron
Catalysed by KDSR
7 names
Resolves to: KDSR
Rhea RHEA:22640CC BY 4.0Reference data