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Proteins/UNIPROT:Q92482
Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. Could also be permeable to urea (By similarity). Also participates in cell permeability to H2O2 and H2O2-mediated signaling. In skin, transports glycerol to the epidermis and stratum corneum, where it maintains hydration, elasticity, and supports lipid biosynthesis for barrier repair (By similarity). In kidney, contributes to the reabsorption of water, helping the body maintain proper fluid balance (By similarity)..
Function from UniProtKB (Q92482), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
105 statements
105 statements · 8 reference databases · Subject: AQP3 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
7 reactions
2 names
Resolves to: AQP3
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04885CC BY 4.0Reference data
MAM01983e+waterMAM01983c+water
Transported by AQP9 or AQP10 or AQP7 or AQP3
Reaction pageReversibleBalancedextracellular space, cytosol
Human-GEM MAR09890CC BY 4.0Reference data
Transported by AQP7B or AQP12B or AQP7 or AQP9 or AQP8 or AQP1 or MIP or AQP2 or AQP5 or AQP4 or CLDN15 or CLDN2 and 5 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:29667CC BY 4.0Reference data
Transported by AQP7B or AQP7 or AQP9 or AQP1 or AQP2 or AQP11 or AQP3 or AQP10
Reaction pageDirection not assertedBalanced
Rhea RHEA:29675CC BY 4.0Reference data
Transported by AQP7 or AQP9 or SLC14A1 or SLC14A2 or AQP3 or AQP10
Reaction pageDirection not assertedBalanced
Rhea RHEA:32799CC BY 4.0Reference data
hydrogen peroxidehydrogen peroxide
Transported by AQP9 or AQP8 or AQP1 or AQP11 or AQP3
Reaction pageDirection not assertedBalanced
Rhea RHEA:74375CC BY 4.0Reference data