autosomal dominant striatal neurodegeneration type 1

Findings

No curated finding names autosomal dominant striatal neurodegeneration type 1 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.

Definition

Inheritance

Autosomal dominant inheritance

Onset and course

Middle age onset · Slowly progressive

HPO, annotations 2026-09-02

What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.

Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.

Where it sits

A kind of

• parkinsonian disorder
• striatal degeneration, autosomal dominant

Resolves to: autosomal dominant striatal neurodegeneration type 1

Also called

ADSD1PDE8B striatal degeneration, autosomal dominantstriatal Degeneration, autosomal dominant 1striatal degeneration, autosomal dominant caused by mutation in PDE8B