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Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed

Atlas Graph Access

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Atlas Graph Access Compounds Outcomes Proteins Interactions Papers Articles Pathways Processes Anatomy Cell types Organisms Materials Assessments

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Catalyst

The evidence graph for human biochemistry. Every edge carries its source, its study design, and a grade computed from both.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
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Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments

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Mission
Method
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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Reaction

3',5'-cyclic AMP+waterAMP+hydron

Left to right · Balance undeterminable

Inferred

Reference data, not a finding. Evidence key

Catalysts

PDE2A
PDE8A
PDE8B
ENPP1
PDE4A
PDE1A
PDE1B
PDE4B
PDE4C
PDE4D
PDE3B
PDE7A
PDE1C
PDE3A
PRUNE1
PDE11A
PDE7B
PDE10A

Rhea RHEA:25277·2026-08-19·CC BY 4.0Reference data