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Proteins/UNIPROT:Q9HCR9
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively..
Function from UniProtKB (Q9HCR9), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
26 statements
26 statements · 7 reference databases · Subject: PDE11A · Sources: gene ontology, Hetionet, Human-GEM, Reactome, Rhea, UniProt, WikiPathways
7 reactions
1 name
Resolves to: PDE11A
Human-GEM MAR04014CC BY 4.0Reference data
3',5'-cyclic GMP+waterGMP+proton
Catalysed by PDE8A or PDE6C or PDE10A or PDE8B or PDE4D or PDE1A or PDE1B or PDE11A or PDE6A or PDE6B or PDE5A or PDE6H and 7 more alternatives
Reaction pageLeft to rightBalancedEC 3.1.4.17, 3.1.4.35cytosol
Human-GEM MAR04048CC BY 4.0Reference data
3',5'-cyclic GMP+waterGMP+proton
Catalysed by PDE6C or PDE4C or PDE10A or PDE4D or PDE1A or PDE1B or PDE11A or PDE6A or PDE6B or PDE5A or PDE6H or PDE3B and 7 more alternatives
Reaction pageLeft to rightBalancedEC 3.1.4.35nucleus
Human-GEM MAR08083CC BY 4.0Reference data
3',5'-cyclic GMP+waterGMP+proton
Catalysed by PDE8A or PDE6C or PDE4C or PDE10A or PDE4D or PDE1A or PDE1B or PDE11A or PDE6A or PDE6B or PDE5A or PDE6H and 6 more alternatives
Reaction pageLeft to rightBalancedEC 3.1.4.17Golgi apparatus
Human-GEM MAR08085CC BY 4.0Reference data
3',5'-cyclic AMP+waterAMP+proton
Catalysed by PDE4A or PDE8A or PDE4C or PDE10A or PDE8B or PDE4D or PDE1A or PDE1B or PDE11A or PDE6H or PDE3B or PDE1C and 6 more alternatives
Reaction pageLeft to rightBalancedEC 3.1.4.17Golgi apparatus
Human-GEM MAR08087CC BY 4.0Reference data
3',5'-cyclic GMP+waterGMP+hydron
Catalysed by PDE2A or PDE5A or PDE9A or PDE6A or PDE6B or PDE6C or PDE1A or PDE1B or PDE3B or PDE6H or PDE1C or PDE3A and 3 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:16957CC BY 4.0Reference data
3',5'-cyclic AMP+waterAMP+hydron
Catalysed by PDE2A or PDE8A or PDE8B or ENPP1 or PDE4A or PDE1A or PDE1B or PDE4B or PDE4C or PDE4D or PDE3B or PDE7A and 6 more alternatives
Reaction pageLeft to rightBalanced
Rhea RHEA:25277CC BY 4.0Reference data