Pathway
EGFR tyrosine kinase inhibitor resistance
Tyrosine kinase inhibitors (TKIs) are drugs that inhibit the phosphorylation, and subsequent activation, of tyrosine kinases. TKIs are typically used as cancer therapeutics, but development of resi...
WP:4806
What the reference databases state
Statements
84 statements
84 statements · 1 reference database · Subject: EGFR tyrosine kinase inhibitor resistance · Sources: WikiPathways
- AKT1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- AKT2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- AKT3 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- ARAF participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- AXL participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- BAD participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- BAX participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- BCL2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- BCL2L1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- BCL2L11 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- BRAF participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- CCND1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
Show the remaining 72
- EGF participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- EGFR participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- EIF4E participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- EIF4E2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- EIF4EBP1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- ERBB2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- ERBB3 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- FGF2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- FGFR2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- FGFR3 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- FOXO3 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- GAB1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- GAS6 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- GRB2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- GSK3B participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- HGF participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- HRAS participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- IGF1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- IGF1R participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- IL6 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- IL6R participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- JAK1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- JAK2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- KDR participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- KRAS participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- MAP2K1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- MAP2K2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- MAPK1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- MAPK3 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- MET participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- MRAS participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- MTOR participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- MYC participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- NF1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- NRAS participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- NRG1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- NRG2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PDGFA participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PDGFB participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PDGFC participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PDGFD participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PDGFRA participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PDGFRB participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PDPK1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PIK3CA participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PIK3CB participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PIK3CD participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PIK3R1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PIK3R2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PIK3R3 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PLCG1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PLCG2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PRKCA participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PRKCB participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PRKCG participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- PTEN participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- RAF1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- RPS6 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- RPS6KB1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- RPS6KB2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- RRAS participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- RRAS2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- SHC1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- SHC2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- SHC3 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- SHC4 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- SOS1 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- SOS2 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- SRC participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- STAT3 participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- TGFA participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only
- VEGFA participates in EGFR tyrosine kinase inhibitor resistanceProteinWikiPathways WP4806Inferred only