Pathway
Synthesis of PC
De novo (Kennedy pathway) synthesis of phosphatidylcholine (PC) involves phosphorylation of choline (Cho) to phosphocholine (PCho) followed by condensing with cytidine triphosphate (CTP) to form CDP-choline (CDP-Cho). Diacylglycerol (DAG) and CDP-ETA together then form PC. Alternatively, PC is formed when phosphatidylethanolamine (PE) is methylated by phosphatidylethanolamine N-methyltransferase (PEMT).
REACT:R-HSA-1483191Reactome
What the reference databases state
Statements
28 statements
28 statements · 1 reference database · Subject: Synthesis of PC · Sources: Reactome
- ABHD3 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- ACHE participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- BCHE participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- CEPT1 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- CHAT participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- CHKA participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- CHKB participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- CHPT1 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- CSNK2A1 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- CSNK2A2 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- CSNK2B participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- LPCAT1 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
Show the remaining 16
- LPIN1 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- LPIN2 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- LPIN3 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- MFSD2A participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- PCTP participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- PCYT1A participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- PCYT1B participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- PEMT participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- PHOSPHO1 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- SLC44A1 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- SLC44A2 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- SLC44A3 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- SLC44A4 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- SLC44A5 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- STARD10 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only
- STARD7 participates in Synthesis of PCProteinReactome R-HSA-1483191Inferred only