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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q8WWI5

SLC44A1

Protein·UNIPROT:Q8WWI5Choline transporter-like protein 11 compound

Open in the graph

Choline/H+ antiporter. Also acts as a high-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the CDP-Etn pathway, redistribute intracellular Etn and balance the CDP-Cho and CDP-Etn arms of the Kennedy pathway. Involved in membrane synthesis and myelin production..

Function from UniProtKB (Q8WWI5), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 1 · transported by

Inferred

Assembled routes, not reported.

What routes through it

1 compound

1 compound.

0 reported routes1 assembled route

cholineCompoundCHEBI:15354Inferred only128 paths62 endpoints

What the reference databases state

GenCC submitters' classifications

1 row

neurodegeneration, childhood-onset, with ataxia, tremor, optic atrophy, and cognitive decline has a germline basis in SLC44A1DiseaseGenCC HGNC:18798|MONDO:0030028Inferred only

Statements

85 statements

85 statements · 7 reference databases · Subject: SLC44A1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways

Search this listOrder

SLC44A1 is expressed in Ammon's hornAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in amygdalaAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in bone marrowAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in breastAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in bronchusAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in C1 segment of cervical spinal cordAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in caput epididymisAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in cauda epididymisAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in caudate nucleusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in cerebral cortexAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in colonAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in corpus callosumAnatomyBgee ENSG00000070214Inferred only

Show the remaining 73

SLC44A1 is expressed in corpus epididymisAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in deciduaAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in duodenumAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in endometriumAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in endothelial cellCell typeBgee ENSG00000070214Inferred only
SLC44A1 is expressed in epididymisAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in fallopian tubeAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in gallbladderAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in gingivaAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in gingival epitheliumAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in globus pallidusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in inferior vagus X ganglionAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in jejunal mucosaAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in lateral globus pallidusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in lateral nuclear group of thalamusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in lower lobe of lungAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in mammalian vulvaAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in mammary ductAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in medial globus pallidusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in medulla oblongataAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in mucosa of sigmoid colonAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in nippleAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in pancreasAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in parathyroid glandAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in parietal lobeAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in penisAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in pericardiumAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in placentaAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in ponsAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in postcentral gyrusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in putamenAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in pylorusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in rectumAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in rectumAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in seminal vesicleAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in seminal vesicleAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in skin of hipAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in Small intestineAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in spinal cordAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in stomachAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in substantia nigra pars compactaAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in substantia nigra pars reticulataAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in subthalamic nucleusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in superior vestibular nucleusAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in tibiaAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in tonsilAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in trabecular bone tissueAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in trigeminal ganglionAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in upper leg skinAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in urinary bladderAnatomyHuman Protein Atlas ENSG00000070214Inferred only
SLC44A1 is expressed in ventral tegmental areaAnatomyBgee ENSG00000070214Inferred only
SLC44A1 is expressed in vermiform appendixAnatomyHuman Protein Atlas ENSG00000070214Inferred only
KCNE3 interacts with SLC44A1ProteinHetionet hetionet:interacts:10008-23446Inferred only
NUDT21 interacts with SLC44A1ProteinHetionet hetionet:interacts:11051-23446Inferred only
SMAP interacts with SLC44A1ProteinHetionet hetionet:interacts:10944-23446Inferred only
UBC interacts with SLC44A1ProteinHetionet hetionet:interacts:23446-7316Inferred only
SLC44A1 participates in Choline catabolismPathwayReactome R-HSA-6798163Inferred only
SLC44A1 participates in Diet dependent trimethylamine trimethylamine N oxide metabolism PathwayWikiPathways WP5219Inferred only
SLC44A1 participates in Glycerophospholipid biosynthesisPathwayReactome R-HSA-1483206Inferred only
SLC44A1 participates in MetabolismPathwayReactome R-HSA-1430728Inferred only
SLC44A1 participates in Metabolism of amino acids and derivativesPathwayReactome R-HSA-71291Inferred only
SLC44A1 participates in Metabolism of lipidsPathwayReactome R-HSA-556833Inferred only
SLC44A1 participates in Phospholipid metabolismPathwayReactome R-HSA-1483257Inferred only
SLC44A1 participates in SLC-mediated bile acid transportPathwayReactome R-HSA-9958517Inferred only
SLC44A1 participates in SLC-mediated transmembrane transportPathwayReactome R-HSA-425407Inferred only
SLC44A1 participates in SLC-mediated transport of organic anionsPathwayReactome R-HSA-9955298Inferred only
SLC44A1 participates in Synthesis of PCPathwayReactome R-HSA-1483191Inferred only
SLC44A1 participates in Transport of small moleculesPathwayReactome R-HSA-382551Inferred only
choline is transported by SLC44A1CompoundHuman-GEM MAR04954Inferred only
choline is transported by SLC44A1CompoundRhea RHEA:75463Inferred only
ethanolamine is transported by SLC44A1CompoundRhea RHEA:75467Inferred only
hydron is transported by SLC44A1CompoundRhea RHEA:75463Inferred only
hydron is transported by SLC44A1CompoundRhea RHEA:75467Inferred only

Reactions

3 reactions

cholinecholine
Transported by SLC44A1 or SLC22A2 or SLC44A2 or SLC44A5 or SLC44A3 or SLC22A1 or SLC22A5 or SLC44A4
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04954CC BY 4.0Reference data
choline+nhydroncholine+

Other names

5 names

Resolves to: SLC44A1

Also called: CD antigen CD92CD92CDW92CTL1Solute carrier family 44 member 1

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Transported by SLC44A4 or SLC44A2 or SLC44A5 or SLC44A1

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:75463CC BY 4.0Reference data

ethanolamine+nhydronethanolamine+nhydron

Transported by SLC44A2 or SLC44A1

Reaction pageDirection not assertedBalance undeterminable

Rhea RHEA:75467CC BY 4.0Reference data