succinyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

185 compounds within 3 steps: 7 in 1, 16 in 2, 162 in 3

Three steps

(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 5 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 7 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 5 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 6 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 6 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 8 routes
heptadecanoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 7 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 6 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 6 routes
nonadecanoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 7 routes
(11Z)-octadecenoyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 3 moremitochondrial matrix, cytosolOne of 3 routes
a 2,3-diacyl-sn-glycerolReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 4 more
1-O-alkyl-3-acylglycerolReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. 1-O-alkylglycerol + an acyl-CoA = 1-O-alkyl-3-acylglycerol + CoA
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 4 more
dodecanedioyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Activation of dodecanedioic acid
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2mitochondrial matrix, cytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Production of Sebacoylcarnitine
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 3 moremitochondrial matrix, cytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Production of Suberylcarnitine
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 3 moremitochondrial matrix, cytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 8 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 6 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 3 moremitochondrial matrix, cytosol
(13Z)-eicosenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 6 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 2 moremitochondrial matrix, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 4 moremitochondrial matrix, peroxisome
hexadecanedioyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Production of Hexadecanedioylcarnitine
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 3 moremitochondrial matrix, cytosolOne of 2 routes
pristanoyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. fatty-acid-CoA ligase
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 1 moremitochondrial matrix, cytosolOne of 2 routes
a 1,3-diacyl-sn-glycerolReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. a 3-acyl-sn-glycerol + an acyl-CoA = a 1,3-diacyl-sn-glycerol + CoA
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 3 moreOne of 2 routes
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholineReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphocholine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphocholine + CoA
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 4 more
a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamineReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. a 1-O-(1Z-alkenyl)-sn-glycero-3-phosphoethanolamine + an acyl-CoA = a 1-O-(1Z-alkenyl)-2-acyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 3 more
undecanoyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 6 moremitochondrial matrix, cytosolOne of 3 routes
17beta-estradiol 17-O-(beta-D-glucuronate)Reach from here →
1. glutarate + succinyl-CoA = glutaryl-CoA + succinate
2. glutaryl-CoA + H2O = glutarate + CoA + H(+)
3. 17beta-estradiol 17-O-(beta-D-glucuronate)(out) + glutarate(in) = 17beta-estradiol 17-O-(beta-D-glucuronate)(in) + glutarate(out)
Catalysed by SUGCT, ACOT8, ACOT4, SLC22A24inner side of the membrane, outer side of the membraneOne of 2 routes
(5Z)-tetradecenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 9 routes
(3E)-decenoyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 4 moremitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. itaconate + succinyl-CoA = itaconyl-CoA + succinate
2. Itaconate:CoA ligase (GDP-forming)
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by SUGCT, SUCLG1, SUCLG2, SUCLA2 and 3 moremitochondrial matrix
an N(2)-acyl-L-glutamineReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. an acyl-CoA + L-glutamine = an N(2)-acyl-L-glutamine + CoA + H(+)
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 4 more
(7Z)-hexadecenoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 9 routes
tricosanoyl-CoAReach from here →
1. a 3-oxo acid + succinyl-CoA = a 3-oxoacyl-CoA + succinate
2. an acyl-CoA + acetyl-CoA = a 3-oxoacyl-CoA + CoA
3. acyl-CoA pool formation and breakdown
Catalysed by OXCT1, OXCT2, ACAA1, SCP2 and 2 morecytosolOne of 5 routes