serotonin

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

763 compounds within 3 steps: 10 in 1, 169 in 2, 584 in 3

Three steps

1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. dodecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 5 morecytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 5 morecytosol
1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. a 1-acyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA = 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
3. nonadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 8 morecytosol
1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
3. (11Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by AANAT, CPT1A, CPT1C, CPT1B and 2 morecytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA = 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octadecanoyl-CoA = 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 5 morecytosol
1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
1. transport of serotonin (cytosol to extracellular)
2. transport of arachidonate (cytosol to extracellular)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
Catalysed by SLCO1A2, SLCO1B3, SLCO1B1, ALOX12Bextracellular space, cytosol
1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. octanoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by AANAT, CROT, LPCAT4cytosol, mitochondrial matrix
1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + octadecanoyl-CoA = 1-acyl-2-octadecanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 5 morecytosol
1-hexadecanoyl-2-decanoyl-sn-glycero-3-phosphocholineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. medium-chain acyl-CoA ligase (decanoic acid)
3. decanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-decanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by AANAT, ACSM4, ACSM1, ACSM2A and 4 morecytosol
1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. octanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by AANAT, CROT, LPCAT1cytosol, mitochondrial matrix
1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. tetradecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-tetradecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoateReach from here →
1. transport of serotonin (cytosol to extracellular)
2. transport of arachidonate (cytosol to extracellular)
3. Arachidonate:oxygen 8-oxidoreductase
Catalysed by SLCO1A2, SLCO1B3, SLCO1B1, ALOX12extracellular space, cytosolOne of 2 routes
a 2,3-diacyl-sn-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. acyl-CoA:sphingosine N-acyltransferase
3. a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA
Catalysed by AANAT, ASAH1, ACER2, ACER1 and 3 morecytosol, Golgi apparatus
1-dodecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 2-(9Z-octadecenoyl)-glycerol + dodecanoyl-CoA = 1-dodecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (myristic acid)
3. 2-(9Z-octadecenoyl)-glycerol + tetradecanoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. 2-(9Z-octadecenoyl)-glycerol + octadecanoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 2-(9Z-octadecenoyl)-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z,12Z-octadecadienoyl)-2-(9Z-octadecenoyl)-glycerol + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
eicosan-1-olReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 2 NADPH + 2 H(+) = eicosan-1-ol + 2 NADP(+) + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
hexadecyl (9Z)-hexadecenoateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. hexadecan-1-ol + (9Z)-hexadecenoyl-CoA = hexadecyl (9Z)-hexadecenoate + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
hexadecyl octadecanoateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (stearate)
3. hexadecan-1-ol + octadecanoyl-CoA = hexadecyl octadecanoate + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
2-O-(5Z,8Z,11Z,14Z)-eicosatetraenylglycerolReach from here →
1. transport of serotonin (cytosol to extracellular)
2. transport of arachidonate (cytosol to extracellular)
3. fatty acid amide hydrolase (arachidonate)
Catalysed by SLCO1A2, SLCO1B3, SLCO1B1, FAAHextracellular space, cytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by AANAT, CROT, LCLAT1cytosol, mitochondrial matrix
1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Octanoyl-CoA:L-carnitine O-octanoyltransferase
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by AANAT, CROT, LCLAT1cytosol, mitochondrial matrix
1-O-alkyl-3-acylglycerolReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. acyl-CoA:sphingosine N-acyltransferase
3. 1-O-alkylglycerol + an acyl-CoA = 1-O-alkyl-3-acylglycerol + CoA
Catalysed by AANAT, ASAH1, ACER2, ACER1 and 3 morecytosol, Golgi apparatus
hexadecanedioateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Production of Hexadecanedioylcarnitine
3. hexadecanedioyl-CoA + H2O = hexadecanedioate + CoA + H(+)
Catalysed by AANAT, CPT1A, CPT1C, CPT1B and 1 morecytosol
(2E,8Z,11Z,14Z)-eicosatetraenoyl-CoAReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
3. ELOVL fatty acid elongase (trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA)
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol, endoplasmic reticulumOne of 2 routes
3-oxo-(11Z)-octadecenoyl-CoAReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (palmitolate)
3. (9Z)-hexadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z)-octadecenoyl-CoA + CO2 + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
3-oxo-(13Z)-eicosenoyl-CoAReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
3. (11Z)-octadecenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(13Z)-eicosenoyl-CoA + CO2 + CoA
Catalysed by AANAT, CPT1A, CPT1C, CPT1B and 1 morecytosol
11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →
1. transport of serotonin (cytosol to extracellular)
2. transport of arachidonate (cytosol to extracellular)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by SLCO1A2, SLCO1B3, SLCO1B1, CYP2C9extracellular space, cytosol
19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. transport of serotonin (cytosol to extracellular)
2. transport of arachidonate (cytosol to extracellular)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by SLCO1A2, SLCO1B3, SLCO1B1, CYP1A1 and 4 moreextracellular space, cytosol
20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. transport of serotonin (cytosol to extracellular)
2. Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5
3. 10-HETE[n] + NAD+[n] = H+[n] + NADH[n] + 20-oxo-(5Z,8Z,11Z,14Z)-eicosatetraenoate[n]
Catalysed by SLCO1A2, SLCO1B3, SLCO1B1, ADH4extracellular space, cytosol, nucleusOne of 3 routes
1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-(9Z-octadecenoyl)-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
O-dodecanoyl-R-carnitineReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. Carnitine O-Palmitoyltransferase
3. carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by AANAT, CPT1A, CPT1C, CPT1BcytosolOne of 11 routes
1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol
(11Z,14Z)-eicosadienoateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
3. (11Z,14Z)-eicosadienoyl-CoA hydrolase
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 8 morecytosol
(17Z)-hexacosenoateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
3. Hexacosenoyl-CoA hydrolase
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoateReach from here →
1. acetyl-CoA:aralkylamine N-acetyltransferase
2. long-chain-fatty-acid-CoA ligase (DPA)
3. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoA hydrolase
Catalysed by AANAT, SLC27A2, ACSL4, ACSL3 and 7 morecytosol