2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

84 compounds within 3 steps: 2 in 1, 8 in 2, 74 in 3

Three steps

(5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (5S)-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate
Catalysed by GDPD2, FAAH, ALOX5cytosol
leukotriene A4Reach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = leukotriene A4 + H2O
Catalysed by GDPD2, FAAH, ALOX5cytosol
sn-glycerol 3-phosphateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
3. glycerol + ATP = sn-glycerol 3-phosphate + ADP + H(+)
Catalysed by GDPD2, FAAH, CES2, ABHD16A and 12 moreOne of 2 routes
sn-glycerol 1-phosphateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
3. sn-glycerol 1-phosphate + H2O = glycerol + phosphate
Catalysed by GDPD2, FAAH, CES2, ABHD16A and 9 more
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. 1D-myo-inositol 1-phosphate phosphohydrolase
3. a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)
Catalysed by GDPD2, IMPA2, IMPA1, CDIPTcytosol
6-phospho-D-glucono-1,5-lactoneReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. inositol-3-phosphate synthase (inositol-1-phosphate)
3. D-glucose-6-phosphate:NADP+ 1-oxidoreductase
Catalysed by GDPD2, ISYNA1, G6PDcytosol, endoplasmic reticulumOne of 3 routes
1D-myo-inositol 3-phosphateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. inositol-3-phosphate synthase (inositol-1-phosphate)
3. 1D-myo-inositol-3-phosphate lyase (isomerizing)
Catalysed by GDPD2, ISYNA1cytosol
D-glucuronateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. 1D-myo-inositol 1-phosphate phosphohydrolase
3. myo-inositol + O2 = D-glucuronate + H2O + H(+)
Catalysed by GDPD2, IMPA2, IMPA1, MIOXcytosol
N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycineReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine
Catalysed by GDPD2, FAAH, PM20D1cytosol
18-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. cytochrome P450 (arachidonate)
Catalysed by GDPD2, FAAH, CYP4F8cytosol, endoplasmic reticulumOne of 2 routes
1-octadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
3. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by GDPD2, FAAH, CES2, ABHD16A and 9 moreOne of 2 routes
(12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (12R)-hydroperoxy-(5Z,8Z,10E,14Z)-eicosatetraenoate
Catalysed by GDPD2, FAAH, ALOX12Bcytosol
(8S)-hydroperoxy-(5Z,9E,11Z,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. Arachidonate:oxygen 8-oxidoreductase
Catalysed by GDPD2, FAAH, ALOX12cytosolOne of 2 routes
1-(9Z,12Z,15Z-octadecatrienoyl)-glycerolReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
3. 1-octadecanoyl-2-(9Z,12Z,15Z-octadecatrienoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(9Z,12Z,15Z-octadecatrienoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by GDPD2, FAAH, CES2, ABHD16A and 9 more
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerolReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = glycerol + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
3. 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + glycerol = 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1-octadecanoyl-sn-glycero-3-phosphocholine
Catalysed by GDPD2, FAAH, CES2, ABHD16A and 9 more
2-O-(5Z,8Z,11Z,14Z)-eicosatetraenylglycerolReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. fatty acid amide hydrolase (arachidonate)
Catalysed by GDPD2, FAAHcytosol
20-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. arachidonic acid:oxygen 1-oxidoreductase
Catalysed by GDPD2, FAAH, CYP1A1, CYP1A2 and 25 morecytosolOne of 3 routes
11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 11,12-epoxy-(5Z,8Z,14Z)-eicosatrienoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by GDPD2, FAAH, CYP2C9cytosol
19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = 19-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by GDPD2, FAAH, CYP1A1, CYP1A2 and 3 morecytosol
(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O
Catalysed by GDPD2, FAAH, PTGS2cytosolOne of 2 routes
(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O
Catalysed by GDPD2, FAAH, PTGS2cytosolOne of 2 routes
(15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = (15R)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
Catalysed by GDPD2, FAAH, PTGS2cytosol
11R-hydroperoxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. Arachidonate: oxygen 11-oxidoreductase
Catalysed by GDPD2, FAAH, ALOX12cytosolOne of 2 routes
prostaglandin G2Reach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. Arachidonate:oxygen oxidoreductase
Catalysed by GDPD2, FAAH, PTGS1, PTGS2cytosol, endoplasmic reticulumOne of 2 routes
(12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (12R)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by GDPD2, FAAH, CYP2C9cytosol
14,15-epoxy-(5Z,8Z,11Z)-eicosatrienoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. unspecific monooxygenase (arachidonate)
Catalysed by GDPD2, FAAH, CYP1A1, CYP1A2 and 25 morecytosolOne of 4 routes
8,9-epoxy-(5Z,11Z,14Z)-eicosatrienoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. unspecific monooxygenase (arachidonate)
Catalysed by GDPD2, FAAH, CYP1A1, CYP1A2 and 24 morecytosolOne of 3 routes
1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserineReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoserine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoserine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Catalysed by GDPD2, FAAH, ABHD16Acytosol
1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholineReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphocholine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Catalysed by GDPD2, FAAH, ABHD16Acytosol
1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. 1-heptadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphoethanolamine + H2O = 1-heptadecanoyl-sn-glycero-3-phosphoethanolamine + (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+)
Catalysed by GDPD2, FAAH, ABHD16Acytosol
2-glyceryl-prostaglandin H2Reach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 2 O2 = 2-glyceryl-prostaglandin G2
3. 2-glyceryl-prostaglandin G2 + AH2 = 2-glyceryl-prostaglandin H2 + A + H2O
Catalysed by GDPD2, PTGS2
(18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + reduced [NADPH--hemoprotein reductase] + O2 = (18R)-hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by GDPD2, FAAH, CYP4F8cytosol
15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 15-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate
Catalysed by GDPD2, FAAH, ALOX15Bcytosol
5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoateReach from here →
1. 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = 2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + 1D-myo-inositol 1-phosphate + H(+)
2. fatty acid amide hydrolase (2-arachidonoylglycerol)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + O2 = 5-hydroperoxy-(6E,8Z,11Z,14Z)-eicosatetraenoate
Catalysed by GDPD2, FAAH, ALOX15Bcytosol