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D-glucuronate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

Inferred

Every route here is a hypothesis drawn from reference reactions (Rhea and Human-GEM), not a finding. Currency species such as water, ATP and NAD(H) never form a step. Evidence key

14 compounds within 3 steps: 1 in 1, 2 in 2, 11 in 3

Does it reach a compound?

One step

myo-inositolReach from here →
1. myo-inositol + O2 = D-glucuronate + H2O + H(+)
Catalysed by MIOX

Two steps

1-phosphatidyl-1D-myo-inositolReach from here →
1. myo-inositol + O2 = D-glucuronate + H2O + H(+)
2. CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
Catalysed by MIOX, CDIPTcytosolOne of 2 routes
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. myo-inositol + O2 = D-glucuronate + H2O + H(+)
2. a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)
Catalysed by MIOX, CDIPT

Three steps

phosphatidic acidReach from here →
Catalysed by MIOX, CDIPT, PLD2cytosolOne of 3 routes
a 1,2-diacyl-sn-glycerolReach from here →
Catalysed by MIOX and 12 more

cytosol

One of 3 routes

a fatty acidReach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+)

Catalysed by MIOX, CDIPT, DDHD1

a 6-(N-acetyl-alpha-D-glucosaminyl)-1-(1,2-diacyl-sn-glycero-3-phospho)-1D-myo-inositolReach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
phosphatidylinositol N-acetylglucosaminyltransferase (PI pool)

Catalysed by MIOX, CDIPT, PIGA, PIGP and 5 morecytosol, endoplasmic reticulumOne of 3 routes

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-5-phosphate)Reach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
1-phosphatidylinositol-4-phosphate 5-kinase (PI pool)

Catalysed by MIOX, CDIPT, PIP5K1B, PIP5K1C and 2 morecytosolOne of 5 routes

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate)Reach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
ATP:1-phosphatidyl-1D-myo-inositol 3-phosphotransferase

Catalysed by MIOX, CDIPT, PIK3C3cytosolOne of 4 routes

a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)Reach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
ATP:1-Phosphatidyl-1D-myo-inositol 4-phosphotransferase

Catalysed by MIOX, CDIPT, PI4KA, PI4K2B and 2 morecytosolOne of 3 routes

a CDP-1,2-diacyl-sn-glycerolReach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)
a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)

Catalysed by MIOX, CDIPT

1D-myo-inositol 1-phosphateReach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
CDP-diacylglycerol:myo-inositol 3-phosphatidyltransferase
phosphoinositide phospholipase C (PI pool)

Catalysed by MIOX, CDIPT, PLCH2, PLCG2 and 12 morecytosolOne of 3 routes

a 1,2-diacyl-sn-glycero-3-phosphateReach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)
a 1,2-diacyl-sn-glycero-3-phosphate(out) + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(in) = a 1,2-diacyl-sn-glycero-3-phosphate(in) + a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol)(out)

Catalysed by MIOX, CDIPT, PITPNM1inner side of the membrane, outer side of the membraneOne of 2 routes

a 2-acyl-sn-glycero-3-phospho-D-myo-inositolReach from here →

myo-inositol + O2 = D-glucuronate + H2O + H(+)
a CDP-1,2-diacyl-sn-glycerol + myo-inositol = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + CMP + H(+)
a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + H2O = a 2-acyl-sn-glycero-3-phospho-D-myo-inositol + a fatty acid + H(+)

Catalysed by MIOX, CDIPT, DDHD1