CHEBI:15978

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

624 compounds within 3 steps: 11 in 1, 138 in 2, 475 in 3

Two steps

1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
2. 1-hexadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-hexadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol
(5Z,8Z,11Z,14Z,17Z)-eicosapentaenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (EPA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 9 routes
(7Z,10Z,13Z,16Z,19Z)-docosapentaenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (DPA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 6 routes
1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
2. 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
(9Z,12Z,15Z)-octadecatrienoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (linolenate)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 7 routes
(13Z)-docosenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (cis-erucic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 6 routes
(11Z)-eicosenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (cis-gondoic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 7 routes
(9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 5 routes
(6Z,9Z,12Z,15Z,18Z,21Z)-tetracosahexaenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z,12Z,15Z,18Z,21Z)-THA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 4 routes
(15Z)-tetracosenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (nervonic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 6 routes
(17Z)-hexacosenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (ximenic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 4 routes
(8Z,11Z,14Z)-eicosatrienoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 5 routes
(8Z,11Z,14Z,17Z)-eicosatetraenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (omega-3-arachidonic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 5 routes
(4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (DHA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 7 routes
heptadecanoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (margaric acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 6 routes
(9Z)-heptadecenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (9-heptadecylenic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 5 routes
(11Z,14Z,17Z)-eicosatrienoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z,17Z)-eicosatrienoic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 5 routes
1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (linoleoyl-CoA)
2. 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 4 morecytosol
1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (myristoyl-CoA)
2. 1-tetradecanoyl-sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (arachidonyl-CoA)
2. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol
nonadecanoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 6 routes
(11Z)-octadecenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 3 morecytosolOne of 3 routes
1-tetradecanoyl-sn-glycerolReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (myristoyl-CoA)
2. 1-tetradecanoyl-sn-glycerol 3-phosphate + H2O = 1-tetradecanoyl-sn-glycerol + phosphate
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
1-hexadecanoyl-sn-glycerolReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
2. 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = 1-hexadecanoyl-sn-glycerol + phosphate
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
1-octadecanoyl-sn-glycerolReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
2. 1-octadecanoyl-sn-glycero-3-phosphate + H2O = 1-octadecanoyl-sn-glycerol + phosphate
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
dodecanedioyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Activation of dodecanedioic acid
Catalysed by GPAT3, GPAT2, GPAT4, GPAMcytosolOne of 4 routes
decanedioyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Production of Sebacoylcarnitine
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 3 morecytosolOne of 4 routes
octanedioyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Production of Suberylcarnitine
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 3 morecytosolOne of 4 routes
hexanedioyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by GPAT3, GPAT2, GPAT4, GPAMcytosolOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 3 morecytosol
(13Z)-eicosenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 2 morecytosol, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 4 morecytosol, peroxisome
hexadecanedioyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Production of Hexadecanedioylcarnitine
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 3 morecytosolOne of 2 routes
1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (5Z,8Z,11Z,14Z)-eicosatetraenoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
2. 1-octadecanoyl-sn-glycero-3-phosphate + (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA = 1-octadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
pristanoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. fatty-acid-CoA ligase
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosolOne of 2 routes
undecanoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 6 morecytosolOne of 3 routes
hexadecanoateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
2. 1-hexadecanoyl-sn-glycero-3-phosphate + H2O = sn-glycerol 3-phosphate + hexadecanoate + H(+)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 3 morecytosol
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphateReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (palmitoyl-CoA)
2. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphate = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 1 morecytosol
(5Z)-tetradecenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 4 morecytosol, mitochondrial matrix
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 3 morecytosol, mitochondrial matrix
(7Z)-hexadecenoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 8 routes
tricosanoyl-CoAReach from here →
1. glycerol-3-phosphate 1-O-acyltransferase (lauroyl-CoA)
2. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 8 morecytosolOne of 4 routes

Three steps

N(omega)-methyl-L-arginineReach from here →
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 4 morecytosol, mitochondrial matrixOne of 2 routes