palmitoyl-CoA

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

829 compounds within 3 steps: 17 in 1, 232 in 2, 580 in 3

Three steps

1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphateReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. glycerol-3-phosphate 1-O-acyltransferase (linoleoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 13 morecytosolOne of 4 routes
1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z)-octadecadienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, LCLAT1cytosol
1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z,12Z,15Z)-octadecatrienoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(9Z,12Z,15Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, AGPAT2, GPAT3 and 2 morecytosol
1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphateReach from here →
1. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, AGPAT2, GPAT3 and 5 morecytosol
1-heptadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-heptadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-heptadecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, LPCAT2, AGPAT5cytosol
1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphateReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (margaric acid)
3. heptadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-heptadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 14 morecytosol
1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
3. 1-octadecanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-octadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by GPAT3, GPAT2, GPAT4, GPAM and 4 morecytosolOne of 2 routes
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphateReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 15 morecytosol
(6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(6Z,9Z,12Z-octadecatrienoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = (6Z,9Z,12Z)-octadecatrienoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, AGPAT2, GPAT3 and 1 morecytosol
1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-eicosanoyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-eicosanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, AGPAT2, AGPAT1cytosol
1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-tetradecanoyl-sn-glycerol 3-phosphate + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, AGPAT2, GPAT3 and 1 morecytosolOne of 2 routes
3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoAReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((9Z,12Z,15Z,18Z,21Z)-TPA)
3. (9Z,12Z,15Z,18Z,21Z)-tetracosapentaenoyl-CoA + malonyl-CoA + H(+) = 3-oxo-(11Z,14Z,17Z,20Z,23Z)-hexacosapentaenoyl-CoA + CO2 + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by SCD, SCD5, LPCAT3, LPCAT1cytosol
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholineReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by SCD, SCD5, LPCAT3, AGPAT5cytosol
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholineReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
(2E)-eicosenoyl-CoAReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. acyl-CoA oxidase (eicosanoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, peroxisomeOne of 4 routes
(2E)-docosenoyl-CoAReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (behenic acid)
3. acyl-CoA oxidase (docosanoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, peroxisomeOne of 4 routes
(2E)-tetracosenoyl-CoAReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lignocerate)
3. acyl-CoA oxidase (tetracosanoyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol, peroxisomeOne of 3 routes
1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z-octadecenoyl)-2-(9Z,12Z-octadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serineReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z)-octadecenoyl-sn-glycero-3-phospho-L-serine + CoA
Catalysed by SCD, SCD5, LPCAT3, MBOAT1 and 1 morecytosol
1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserineReach from here →
1. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-(9Z)-octadecenoyl-2-hexadecanoyl-sn-glycero-3-phosphoserine + CoA
Catalysed by SCD, SCD5, MBOAT2cytosol
a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-acyl-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, LCLAT1cytosolOne of 2 routes
1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphateReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (eicosanoate)
3. eicosanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-eicosanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphateReach from here →
1. Palmitoyl-CoA hydrolase
2. Arachidonate:CoA ligase (AMP-forming)
3. glycerol-3-phosphate 1-O-acyltransferase (arachidonyl-CoA)
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 13 morecytosolOne of 3 routes
1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphate + (9Z)-octadecenoyl-CoA = 1-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by SCD, SCD5, GPAT3, ABHD5 and 1 morecytosol
1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (DHA)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamineReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by SCD, SCD5, MBOAT1, MBOAT2 and 1 morecytosol
1-dodecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-dodecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-dodecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by SCD, SCD5, LPCAT3, LPCAT1cytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholineReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. dodecanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 11 morecytosol
1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-octadecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-octadecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by SCD, SCD5, LPCAT3, LPCAT1cytosol
1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + hexadecanoyl-CoA = 1-hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by SCD, SCD5, LPGAT1cytosolOne of 2 routes
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1-hexadecanoyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholineReach from here →
1. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-tetradecanoyl-sn-glycero-3-phosphocholine + hexadecanoyl-CoA = 1-tetradecanoyl-2-hexadecanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by SCD, SCD5, LPCAT3, LPCAT1cytosol
1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serineReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. a 1-acyl-sn-glycero-3-phospho-L-serine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phospho-L-serine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamineReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. a 1-acyl-sn-glycero-3-phosphoethanolamine + (9Z,12Z)-octadecadienoyl-CoA = 1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphateReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + dodecanoyl-CoA = 1-(9Z)-octadecenoyl-2-dodecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphateReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (nonadecylic acid)
3. nonadecanoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-nonadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 12 morecytosol
a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. a 1-acyl-sn-glycero-3-phospho-(1D-myo-inositol) + (9Z)-octadecenoyl-CoA = a 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by SCD, SCD5, LCLAT1cytosol
1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphateReach from here →
1. Palmitoyl-CoA hydrolase
2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
3. (11Z)-octadecenoyl-CoA + 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate = 1-(9Z)-octadecenoyl-2-(11Z)-octadecenoyl-sn-glycero-3-phosphate + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 6 morecytosol
1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1-acyl-2-(9Z)-octadecenoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by SCD, SCD5, LCLAT1cytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z)-octadecenoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z)-octadecenoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by SCD, SCD5, LCLAT1cytosol
1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol)Reach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1-hexadecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + dodecanoyl-CoA = 1-hexadecanoyl-2-dodecanoyl-sn-glycero-3-phospho-(1D-myo-inositol) + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-tetradecanoyl-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1-tetradecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by SCD, SCD5, LCLAT1cytosol
1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1,2-di-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by SCD, SCD5, LCLAT1, LPGAT1cytosol
1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol)Reach from here →
1. fatty-acyl-CoA synthase (N-C18:0CoA)
2. octadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-octadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1-acyl-sn-glycero-3-phospho-(1'-sn-glycerol) + (9Z)-octadecenoyl-CoA = 1-acyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-sn-glycerol) + CoA
Catalysed by SCD, SCD5, LCLAT1cytosol
1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA = 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase (lauric acid)
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + dodecanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerolReach from here →
1. Palmitoyl-CoA hydrolase
2. long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
3. 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by ACOT7, BAAT, THEM4, ACOT1 and 10 morecytosol
1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
1. palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
2. hexadecanoyl-CoA + 2 Fe(II)-[cytochrome b5] + O2 + 2 H(+) = (9Z)-hexadecenoyl-CoA + 2 Fe(III)-[cytochrome b5] + 2 H2O
3. 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + hexadecanoyl-CoA = 1'-[1-acyl-2-hexadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by SCD, SCD5, LCLAT1cytosol