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Proteins/UNIPROT:Q02094
Component of the ankyrin-1 complex, a multiprotein complex involved in the stability and shape of the erythrocyte membrane. Heterotrimer with RHCE (RHAG)2(RHCE), that transports ammonium and its related derivative methylammonium, in both neutral and ionic forms, across the erythrocyte membrane. The transport of NH4(+) is electrogenic and masks the NH3 transport. Also, may act as a CO2 channel. In vitro, leaks monovalent cations. Moreover in erythrocyte, regulates RHD membrane expression and is associated with rhesus blood group antigen expression..
Function from UniProtKB (Q02094), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
27 statements
27 statements · 6 reference databases · Subject: RHAG · Sources: Bgee, Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
7 reactions
proton+ammoniumproton+ammonium
Reaction pageReversibleBalancedEC 2.7.4.6extracellular space, cytosol
Human-GEM MAR01534CC BY 4.0Reference data
Transported by RHAG
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04873CC BY 4.0Reference data
10 names
Resolves to: RHAG
Transported by RHAG or RHBG or RHCG
Reaction pageReversibleBalancedcytosol, mitochondrial matrix
Human-GEM MAR05022CC BY 4.0Reference data
Transported by RHAG
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05023CC BY 4.0Reference data
Transported by KCNK1 or AQP9 or CNGA1 or CHRNA7 or CLDN15 or CLDN10 or RHAG or AQP6 or CNGB1 or CNGA2 or CNGA3 or CNGA4 and 4 more alternatives
Reaction pageReversibleBalanced
Rhea RHEA:28747CC BY 4.0Reference data
Transported by AQP8 or CLDN15 or CLDN2 or CLDN10 or RHAG or RHBG or RHCG
Reaction pageLeft to rightBalanced
Rhea RHEA:74391CC BY 4.0Reference data
Transported by AQP1 or RHAG or AQP6 or RHBG or RHCG
Reaction pageLeft to rightBalanced
Rhea RHEA:74891CC BY 4.0Reference data