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Proteins/UNIPROT:P56746
Forms paracellular channels: polymerizes in tight junction strands with cation- and water-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability. In intestinal epithelium, allows for sodium and water fluxes from the peritoneal side to the lumen of the intestine to regulate nutrient absorption and intestinal morphogenesis (By similarity)..
Function from UniProtKB (P56746), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 2 · transported by
2 compounds
2 compounds.
0 reported routes2 assembled routes
22 statements
22 statements · 6 reference databases · Subject: CLDN15 · Sources: Bgee, gene ontology, Hetionet, Reactome, Rhea, WikiPathways
8 reactions
1 name
Resolves to: CLDN15
Transported by ANO9 or HTR3E or KCNU1 or KCNJ18 or TMEM150C or KCNK1 or KCNK3 or GRIN2D or KCNN4 or KCNQ3 or KCNQ2 or HCN1 and 136 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:29463CC BY 4.0Reference data
Transported by AQP7B or AQP12B or AQP7 or AQP9 or AQP8 or AQP1 or MIP or AQP2 or AQP5 or AQP4 or CLDN15 or CLDN2 and 5 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:29667CC BY 4.0Reference data
Transported by ANO9 or HTR3E or TMEM150C or KCNK1 or KCNK3 or GRIN2D or GRID2 or KCNQ3 or KCNQ2 or GRIN3B or HCN1 or TRPA1 and 98 more alternatives
Reaction pageRight to leftBalanced
Rhea RHEA:34963CC BY 4.0Reference data
Transported by AQP8 or CLDN15 or CLDN2 or CLDN10 or RHAG or RHBG or RHCG
Reaction pageLeft to rightBalanced
Rhea RHEA:74391CC BY 4.0Reference data
Transported by KCNK1 or KCNQ3 or KCNQ2 or KCNK2 or CNGA1 or CLDN15 or CLDN2 or KCNK10 or CLDN10 or CNGB1 or CNGA2 or CNGA3 and 8 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:78547CC BY 4.0Reference data
Transported by KCNK1 or CNGA1 or GRIA1 or TRPC1 or CLDN15 or CLDN2 or ASIC1 or CLDN10 or CNGB1 or CNGA2 or CNGA3 or ASIC2 and 7 more alternatives
Reaction pageDirection not assertedBalanced
Rhea RHEA:78551CC BY 4.0Reference data