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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:O14829

PPEF1

Protein·UNIPROT:O14829

Open in the graph

Dephosphorylates and destabilises PDCD5 to inhibit TP53/p53-mediated signaling. May have a role in the recovery or adaptation response of photoreceptors (By similarity)..

Function from UniProtKB (O14829), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

3 statements

3 statements · 1 reference database · Subject: PPEF1 · Sources: Hetionet

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CALM1 interacts with PPEF1ProteinHetionet hetionet:interacts:5475-801Inferred only
CALM1 interacts with PPEF1ProteinHetionet hetionet:interacts:5475-808Inferred only
CALM1 interacts with PPEF1ProteinHetionet hetionet:interacts:5475-805Inferred only

Reactions

2 reactions

O-phospho-L-seryl-[protein]+waterL-seryl-[protein]+hydrogenphosphate
Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 61 more alternatives
Reaction pageLeft to rightBalance undeterminable

Other names

7 names

Resolves to: PPEF1

Also called: phosphatase with EF calcium-binding domainPP7PPEFPPEF-1PPP7CProtein phosphatase with EF calcium-binding domainSerine/threonine-protein phosphatase 7

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Rhea RHEA:20629

CC BY 4.0

Reference data

O-phospho-L-threonyl-[protein]+waterL-threonyl-[protein]+hydrogenphosphate

Catalysed by PPP6C or CTDSP2 or PPEF1 or PPEF2 or CTDSPL or PPM1D or PPM1G or PHLPP1 or CDC14B or PPM1B or DUSP14 or EPM2A and 59 more alternatives

Reaction pageLeft to rightBalance undeterminable

Rhea RHEA:47004CC BY 4.0Reference data