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Proteins/UNIPROT:Q9H008
Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity)..
Function from UniProtKB (Q9H008), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
50 statements
50 statements · 3 reference databases · Subject: LHPP · Sources: Hetionet, Reactome, UniProt
6 reactions
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by LHPP or PPA2 or PRUNE1 or PPA1
Reaction pageLeft to rightBalancedEC 3.6.1.1endoplasmic reticulum
Human-GEM MAR03975CC BY 4.0Reference data
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by
1 name
Resolves to: LHPP
Reaction pageLeft to rightBalancedEC 3.6.1.1cytosol
Human-GEM MAR03977CC BY 4.0Reference data
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by LHPP or PPA2 or PRUNE1 or PPA1
Reaction pageLeft to rightBalancedEC 3.6.1.1peroxisome
Human-GEM MAR03979CC BY 4.0Reference data
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by LHPP or PPA2 or PRUNE1 or PPA1
Reaction pageLeft to rightBalancedEC 3.6.1.1mitochondrial matrix
Human-GEM MAR06912CC BY 4.0Reference data
water+diphosphate(3-)proton+2phosphate(3-)
Catalysed by LHPP or PPA2 or PRUNE1 or PPA1
Reaction pageLeft to rightBalancedEC 3.6.1.1nucleus
Human-GEM MAR07794CC BY 4.0Reference data
diphosphate(3-)+water2hydrogenphosphate+hydron
Catalysed by ALPL or PPA1 or LHPP or PPA2
Reaction pageLeft to rightBalanced
Rhea RHEA:24576CC BY 4.0Reference data