dilated cardiomyopathy
MONDO:0005021Mondo
Findings
No curated finding names dilated cardiomyopathy yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Cardiomyopathy which is characterized by dilation and contractile dysfunction of the left and right ventricles. It may be idiopathic, or it may result from a myocardial infarction, myocardial infection, or alcohol abuse. It is a cause of congestive heart failure.
Definition from the Mondo Disease Ontology (MONDO:0005021), read 2026-09-29. CC BY 4.0.
Genes
47 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- FLNCHGNC:3756
- Definitive · Ambry Genetics · Autosomal dominant · 2022
- Definitive · ClinGen · Autosomal dominant · 2025
- Definitive · G2P · Autosomal dominant · 2024
- Strong · PanelApp Australia · Autosomal dominant · 2025
- NRAPHGNC:7988
- Definitive · LiferaOmics · Autosomal recessive · 2026
- Strong · ClinGen · Autosomal recessive · 2024
- Strong · PanelApp Australia · Autosomal recessive · 2025
- PPP1R13LHGNC:18838
- Definitive · G2P · Autosomal recessive · 2020
- RBM20HGNC:27424
- Definitive · ClinGen · Autosomal dominant · 2020
- ACTC1HGNC:143
- Strong · PanelApp Australia · Autosomal dominant · 2025
- HGNC:6648HGNC:6648
- Strong · PanelApp Australia · Autosomal recessive · 2025
- MYPNHGNC:23246
- Strong · PanelApp Australia · Autosomal dominant · 2025
- PPA2HGNC:28883
- Strong · ClinGen · Autosomal recessive · 2025
- PRDM16HGNC:14000
- Strong · ClinGen · Autosomal dominant · 2026
- Strong · PanelApp Australia · Autosomal dominant · 2025
- TBX20HGNC:11598
- Strong · ClinGen · Autosomal dominant · 2026
- HGNC:26424HGNC:26424
- Moderate · Ambry Genetics · Autosomal recessive · 2024
- MYLK3HGNC:29826
- Moderate · Ambry Genetics · Autosomal recessive · 2024
- Moderate · ClinGen · Autosomal dominant · 2025
- Moderate · PanelApp Australia · Autosomal dominant · 2025
- Moderate · PanelApp Australia · Autosomal recessive · 2025
- NEBLHGNC:16932
- Moderate · PanelApp Australia · Autosomal dominant · 2025
- Limited · ClinGen · Autosomal dominant · 2026
- PLEKHM2HGNC:29131
- Moderate · ClinGen · Autosomal recessive · 2024
- Moderate · PanelApp Australia · Autosomal recessive · 2025
- Limited · Ambry Genetics · Autosomal recessive · 2024
- RHBDF1HGNC:20561
- Moderate · PanelApp Australia · Autosomal recessive · 2025
- SLC30A5HGNC:19089
- Moderate · LiferaOmics · Autosomal recessive · 2026
- Limited · Ambry Genetics · Autosomal recessive · 2024
- TNNI3KHGNC:19661
- Moderate · ClinGen · Autosomal dominant · 2026
- ANKRD1HGNC:15819
- Limited · ClinGen · Autosomal dominant · 2025
- BMP10HGNC:20869
- Limited · PanelApp Australia · Autosomal dominant · 2025
- CDH2HGNC:1759
- Limited · ClinGen · Autosomal dominant · 2025
- CEFIPHGNC:26973
- Limited · Ambry Genetics · Autosomal dominant · 2025
- CTF1HGNC:2499
- Limited · ClinGen · Autosomal dominant · 2026
- DTNAHGNC:3057
- Limited · ClinGen · Autosomal dominant · 2026
- FBXO32HGNC:16731
- Limited · Ambry Genetics · Autosomal recessive · 2024
- Limited · ClinGen · Autosomal recessive · 2025
- GATA4HGNC:4173
- Limited · Ambry Genetics · Autosomal dominant · 2021
- GATA6HGNC:4174
- Limited · ClinGen · Autosomal dominant · 2026
- HGNC:15719HGNC:15719
- Limited · ClinGen · Autosomal dominant · 2025
- ILKHGNC:6040
- Limited · ClinGen · Autosomal dominant · 2026
- Limited · PanelApp Australia · Autosomal dominant · 2025
- JPH2HGNC:14202
- Limited · ClinGen · Autosomal dominant · 2025
- MIB1HGNC:21086
- Limited · ClinGen · Autosomal dominant · 2024
- MYBPC3HGNC:7551
- Limited · ClinGen · Autosomal dominant · 2026
- Limited · ClinGen · Autosomal recessive · 2025
- MYL2HGNC:7583
- Limited · ClinGen · Autosomal dominant · 2025
- PHACTR2HGNC:20956
- Limited · Ambry Genetics · Autosomal recessive · 2024
- PPCDCHGNC:28107
- Limited · PanelApp Australia · Autosomal recessive · 2025
- RPL3LHGNC:10351
- Limited · Ambry Genetics · Autosomal recessive · 2020
- RYR2HGNC:10484
- Limited · ClinGen · Autosomal dominant · 2025
- SOD2HGNC:11180
- Limited · PanelApp Australia · Autosomal recessive · 2025
- TCAPHGNC:11610
- Limited · ClinGen · Autosomal dominant · 2025
- TMOD1HGNC:11871
- Limited · ClinGen · Autosomal recessive · 2025
- TXNRD2HGNC:18155
- Limited · Ambry Genetics · Autosomal dominant · 2020
- MYL3HGNC:7584
- Disputed Evidence · ClinGen · Autosomal dominant · 2025
- PDLIM3HGNC:20767
- Disputed Evidence · ClinGen · Autosomal dominant · 2025
- PKP2HGNC:9024
- Disputed Evidence · ClinGen · Autosomal dominant · 2025
- HGNC:11875HGNC:11875
- Refuted Evidence · Ambry Genetics · Autosomal dominant · 2020
- HGNC:20264HGNC:20264
- No Known Disease Relationship · ClinGen · Autosomal recessive · 2024
- NPPAHGNC:7939
- No Known Disease Relationship · ClinGen · Autosomal recessive · 2024
- RTKN2HGNC:19364
- No Known Disease Relationship · ClinGen · Autosomal recessive · 2025
Where it sits
- A kind of