Pathway
Reactions specific to the complex N-glycan synthesis pathway
If MAN2 acts before MGAT3, the pathway progresses to complex N-glycans, because MAN2 is not able to operate on bisected oligosaccharides (11421343, page 5). The expression of MAN2 over MGAT3 in a tissue can regulate the synthesis of hybrid or complex N-glycans.
REACT:R-HSA-975578Reactome
What the reference databases state
Statements
10 statements
10 statements · 1 reference database · Subject: Reactions specific to the complex N-glycan synthesis pathway · Sources: Reactome
- CGA participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- CHST10 participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- CHST8 participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- FUCA1 participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- FUT3 participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- FUT8 participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- LHB participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- MAN2A1 participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- MAN2A2 participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only
- MGAT2 participates in Reactions specific to the complex N-glycan synthesis pathwayProteinReactome R-HSA-975578Inferred only