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A reference for what the literature reports. Not medical advice.

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Proteins/UNIPROT:O14522

PTPRT

Protein·UNIPROT:O14522

Open in the graph

May be involved in both signal transduction and cellular adhesion in the CNS.

Function from UniProtKB (O14522), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

6 statements

6 statements · 3 reference databases · Subject: PTPRT · Sources: gene ontology, Hetionet, WikiPathways

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GRB2 interacts with PTPRTProteinHetionet hetionet:interacts:11122-2885Inferred only
PTPRN interacts with PTPRTProteinHetionet hetionet:interacts:11122-5798Inferred only
PXN interacts with PTPRTProteinHetionet hetionet:interacts:11122-5829Inferred only
PTPRT participates in Regulatory circuits of STAT3 signalingPathwayWikiPathways WP4538Inferred only
PTPRT regulates negative regulation of cell migrationBiological processgene ontology O14522|GO:0030336Inferred only
PTPRT regulates negative regulation of receptor signaling pathway via STATBiological processgene ontology O14522|GO:1904893Inferred only

Reactions

1 reaction

O-phospho-L-tyrosyl-[protein]+waterL-tyrosyl-[protein]+hydrogenphosphate
Catalysed by PGP or EYA2 or PTPRT or CDC14B or PTP4A3 or DUSP14 or EPM2A or EYA4 or PTPRC or PTPRF or ACP3 or PTPN2 and 71 more alternatives
Reaction pageLeft to rightBalance undeterminable

Other names

4 names

Resolves to: PTPRT

Also called: KIAA0283R-PTP-TReceptor-type tyrosine-protein phosphatase rhoRPTP-rho

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Rhea RHEA:10684

CC BY 4.0

Reference data