CHEBI:16668

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

230 compounds within 3 steps: 1 in 1, 12 in 2, 217 in 3

Three steps

(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by BAAT, SLC27A2, ACSL4, ACSL3 and 5 moreextracellular space, peroxisome, cytosolOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by BAAT, CPT1A, CPT1C, CPT1Bextracellular space, peroxisome, cytosol
(13Z)-eicosenoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by BAAT, SLC27A2, ACSL4, ACSL3 and 5 moreextracellular space, peroxisome, cytosolOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by BAAT, CRAT, CROTextracellular space, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by BAAT, ACAA1, HSD17B4, EHHADH and 1 moreextracellular space, peroxisome
hexadecanedioyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. Production of Hexadecanedioylcarnitine
Catalysed by BAAT, CPT1A, CPT1C, CPT1Bextracellular space, peroxisome, cytosolOne of 2 routes
pristanoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. fatty-acid-CoA ligase
Catalysed by BAAT, SLC27A2extracellular space, peroxisome, cytosolOne of 2 routes
undecanoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by BAAT, ACSM4, ACSM1, ACSM2A and 3 moreextracellular space, peroxisome, cytosolOne of 3 routes
(9S)-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (9S)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O
Catalysed by MTO1, PTGS1, PTGS2extracellular space
(9R)-hydroxy-(10E,12Z)-octadecadienoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (9R)-hydroxy-(10E,12Z)-octadecadienoate + A + H2O
Catalysed by MTO1, PTGS1, PTGS2extracellular space
(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (5Z,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
thio-Mo-molybdopterinReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. Mo-molybdopterin + L-cysteine + AH2 = thio-Mo-molybdopterin + L-alanine + A + H2O
Catalysed by MTO1, MOCOSextracellular space
(5Z)-tetradecenoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by BAAT, SLC27A2, ACSL4, ACSL3 and 5 moreextracellular space, peroxisome, cytosolOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by BAAT, ACADM, ECHS1, ACAA2 and 1 moreextracellular space, peroxisome, mitochondrial matrix
2-glyceryl-prostaglandin H2Reach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. 2-glyceryl-prostaglandin G2 + AH2 = 2-glyceryl-prostaglandin H2 + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by BAAT, HADHA, ACAA2, HADHBextracellular space, peroxisome, mitochondrial matrix
(7Z)-hexadecenoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by BAAT, SLC27A2, ACSL4, ACSL3 and 5 moreextracellular space, peroxisome, cytosolOne of 8 routes
tricosanoyl-CoAReach from here →
1. Hypotaurine Oxidase, Extracellular
2. Choloyl-CoA:glycine N-choloyltransferase
3. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by BAAT, SLC27A2, ACSL4, ACSL3 and 5 moreextracellular space, peroxisome, cytosolOne of 4 routes
prostaglandin H1Reach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. prostaglandin G1 + AH2 = prostaglandin H1 + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,11R)-dihydroxy-(6E,8Z,12E,14Z)-eicosatetraenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15R)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (5S)-hydroxy-(6E,8Z,11Z,14Z)-eicosatetraenoate + AH2 + O2 = (5S,15S)-dihydroxy-(6E,8Z,11Z,13E)-eicosatetraenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 17R-hydroxy-(4Z,7Z,10Z,13Z,15E,19Z)-docosahexaenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoate + AH2 + O2 = 13-hydroxy-(4Z,7Z,10Z,14E,16Z,19Z)-docosahexaenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (18R)-hydroxy-(5Z,8Z,11Z,14Z,16E)-eicosapentaenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (15R)-hydroxy-(5Z,8Z,11Z,13E,17Z)-eicosapentaenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (5Z,8Z,11Z,14Z,17Z)-eicosapentaenoate + AH2 + O2 = (11R)-hydroxy-(5Z,8Z,12E,14Z,17Z)-eicosapentaenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (7Z,10Z,13Z,16Z,19Z)-docosapentaenoate + AH2 + O2 = 13R-hydroxy-(7Z,10Z,14E,16Z,19Z)-docosapentaenoate + A + H2O
Catalysed by MTO1, PTGS2extracellular space
(13S)-hydroxy-(9Z,11E)-octadecadienoateReach from here →
1. Hypotaurine Oxidase, Extracellular
2. uridine(34) in tRNA + 5,10-methylenetetrahydrofolate + taurine + GTP + A + H2O = 5-taurinomethyluridine(34) in tRNA + 7,8-dihydrofolate + GDP + AH2 + phosphate + H(+)
3. (9Z,12Z)-octadecadienoate + AH2 + O2 = (13S)-hydroxy-(9Z,11E)-octadecadienoate + A + H2O
Catalysed by MTO1, PTGS1, PTGS2extracellular space