hexadecanoic acid
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
720 compounds within 3 steps: 7 in 1, 152 in 2, 561 in 3
Three steps
- Palmitate:CoA ligase (AMP-forming)
- palmitoyl-CoA desaturase (N-C16:0CoA -> N-C16:1CoA)
- 1-hexadecanoyl-sn-glycero-3-phosphate + (9Z)-hexadecenoyl-CoA = 1-hexadecanoyl-2-[(9Z)-hexadec-9-enoyl]-sn-glycero-3-phosphate + CoA
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosolOne of 2 routes
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol, peroxisomeOne of 2 routes
- Fas180
- glycine N-acyltransferase (N-arachidonoylglycine)
- (2S)-2-aminobutanoate + glyoxylate = 2-oxobutanoate + glycine
Catalysed by GLYAT, GLYATL2, GLYATL1, AGXT2cytosol, mitochondrial matrixOne of 2 routes
- (10Z)-heptadecenoic acid formation
- (10Z)-heptadecenoic acid formation
- N-(15Z-tetracosenoyl)-sphing-4-enine + H2O = (15Z)-tetracosenoate + sphing-4-enine
Catalysed by ACER2, ACER1, ASAH2cytosol, extracellular spaceOne of 2 routes
- Fas180
- acyl-CoA:sphingosine N-acyltransferase
- tetracosenoyl-CoA + sphing-4-enine = N-(tetracosenoyl)-sphing-4-enine + CoA + H(+)
Catalysed by ASAH1, ACER2, ACER1, ASAH2 and 1 morecytosol, Golgi apparatus
- Fas180
- long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
- glycerol-3-phosphate 1-O-acyltransferase (linoleoyl-CoA)
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 8 morecytosolOne of 2 routes
- Palmitate:CoA ligase (AMP-forming)
- fatty-acyl-CoA synthase (N-C18:0CoA)
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + octadecanoyl-CoA = 1-(9Z-octadecenoyl)-2-octadecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 10 morecytosol
- Fas180
- long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + (9Z,12Z)-octadecadienoyl-CoA = 1-(9Z)-octadecenoyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phosphate + CoA
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 10 morecytosol
- Palmitate:CoA ligase (AMP-forming)
- fatty-acyl-CoA synthase (N-C18:0CoA)
- glycerol-3-phosphate 1-O-acyltransferase (sn-glycerol-3-phosphate)
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 8 morecytosolOne of 2 routes
- Palmitate:CoA ligase (AMP-forming)
- Fatty Acid Beta Oxidation (C16->C14), Mitochondrial
- 1-(9Z-octadecenoyl)-sn-glycero-3-phosphate + tetradecanoyl-CoA = 1-(9Z)-octadecenoyl-2-tetradecanoyl-sn-glycero-3-phosphate + CoA
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 12 morecytosol, mitochondrial matrix
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol, peroxisomeOne of 4 routes
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol, peroxisomeOne of 4 routes
Catalysed by SLC27A2, ACSL4, ACSL3, ACSL1 and 6 morecytosol, peroxisomeOne of 3 routes
- 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
- 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerolReach from here →