choline
362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API
807 compounds within 3 steps: 8 in 1, 196 in 2, 603 in 3
Three steps
- 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholineReach from here →
- Acetyl-CoA:choline O-acetyltransferase
- long-chain-fatty-acid-CoA ligase (DHA)
- (4Z,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-(4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by CHAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosolOne of 2 routes
- Acetyl-CoA:choline O-acetyltransferase
- long-chain-fatty-acid-CoA ligase (stearate)
- 2-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-sn-glycero-3-phosphocholine + octadecanoyl-CoA = 1-octadecanoyl-2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-sn-glycero-3-phosphocholine + CoA
Catalysed by CHAT, SLC27A2, ACSL4, ACSL3 and 5 morecytosolOne of 2 routes
- 1'-[1-acyl-2-dodecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-dodecanoyl-sn-glycero-3-phospho]-glycerolReach from here →
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerolReach from here →
- Acetyl-CoA:choline O-acetyltransferase
- long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho]-glycerol + CoA
- 1'-[1-acyl-2-octadecanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
- 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
- Acetyl-CoA:choline O-acetyltransferase
- long-chain-fatty-acid-CoA ligase ((6Z,9Z)-octadecadienoic acid)
- 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + (9Z,12Z)-octadecadienoyl-CoA = 1'-[1-acyl-2-(9Z,12Z)-octadecadienoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
- Acetyl-CoA:choline O-acetyltransferase
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- octanoyl-CoA + a 1-acyl-sn-glycero-3-phosphoethanolamine = 1-acyl-2-octanoyl-sn-glycero-3-phosphoethanolamine + CoA
Catalysed by CHAT, CROT, LPCAT4cytosol, mitochondrial matrix
- Acetyl-CoA:choline O-acetyltransferase
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- octanoyl-CoA + 1-hexadecanoyl-sn-glycero-3-phosphocholine = 1-hexadecanoyl-2-octanoyl-sn-glycero-3-phosphocholine + CoA
Catalysed by CHAT, CROT, LPCAT1cytosol, mitochondrial matrix
- Acetyl-CoA:choline O-acetyltransferase
- acyl-CoA:sphingosine N-acyltransferase
- a 2-acylglycerol + an acyl-CoA = a 2,3-diacyl-sn-glycerol + CoA
Catalysed by CHAT, ASAH1, ACER2, ACER1 and 3 morecytosol, Golgi apparatus
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerolReach from here →
- Acetyl-CoA:choline O-acetyltransferase
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl,2-octanoyl-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by CHAT, CROT, LCLAT1cytosol, mitochondrial matrix
- 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerolReach from here →
- Acetyl-CoA:choline O-acetyltransferase
- Octanoyl-CoA:L-carnitine O-octanoyltransferase
- 1',3'-bis-[1-acyl-sn-glycero-3-phospho]-glycerol + octanoyl-CoA = 1'-[1-acyl-2-octanoyl-sn-glycero-3-phospho],3'-[1-acyl,2-hydroxy-sn-glycero-3-phospho]-glycerol + CoA
Catalysed by CHAT, CROT, LCLAT1cytosol, mitochondrial matrix
- Acetyl-CoA:choline O-acetyltransferase
- acyl-CoA:sphingosine N-acyltransferase
- 1-O-alkylglycerol + an acyl-CoA = 1-O-alkyl-3-acylglycerol + CoA
Catalysed by CHAT, ASAH1, ACER2, ACER1 and 3 morecytosol, Golgi apparatus
- Acetyl-CoA:choline O-acetyltransferase
- long-chain-fatty-acid-CoA ligase (dihomo-gamma-linolenate)
- ELOVL fatty acid elongase (trans-2-cis,cis,cis-8,11,14-eicosatetraenoyl-CoA)
Catalysed by CHAT, SLC27A2, ACSL4, ACSL3 and 6 morecytosol, endoplasmic reticulumOne of 2 routes
- Acetyl-CoA:choline O-acetyltransferase
- transport of acetylcholine (cytosol to extracellular)
- Resistance-Nodulation-Cell Division (Rnd) Tcdb:2.A.60.1.5
Catalysed by CHAT, SLCO1B3, SLCO1B1cytosol, extracellular spaceOne of 4 routes
- Acetyl-CoA:choline O-acetyltransferase
- Carnitine O-Palmitoyltransferase
- carnitine O-palmitoyltransferase (dodecanoylcarnitine)
Catalysed by CHAT, CPT1A, CPT1C, CPT1BcytosolOne of 11 routes