cholesterol sulfate

362,296 routes · scope human · up to 3 steps · built 5 October 2026 · Reactions · API

273 compounds within 3 steps: 2 in 1, 46 in 2, 225 in 3

Three steps

decanedioyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. Production of Sebacoylcarnitine
Catalysed by STS, SOAT2, SOAT1, CPT1A and 2 morecytosol, endoplasmic reticulumOne of 4 routes
octanedioyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. Production of Suberylcarnitine
Catalysed by STS, SOAT2, SOAT1, CPT1A and 2 morecytosol, endoplasmic reticulumOne of 4 routes
hexanedioyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. Activation of adipic acid for Formation of Adipoyl Carnitine
Catalysed by STS, SOAT2, SOAT1cytosol, endoplasmic reticulumOne of 4 routes
(4Z,7Z,10Z,13Z,16Z)-docosapentaenoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. long-chain-fatty-acid-CoA ligase ((4Z,7Z,10Z,13Z,16Z)-DPA)
Catalysed by STS, SOAT2, SOAT1, SLC27A2 and 7 morecytosol, endoplasmic reticulumOne of 7 routes
(11Z,14Z)-eicosadienoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. long-chain-fatty-acid-CoA ligase ((11Z,14Z)-eicosadienoic acid)
Catalysed by STS, SOAT2, SOAT1, SLC27A2 and 7 morecytosol, endoplasmic reticulumOne of 5 routes
(R)-3-hydroxy-(11Z)-octadecenoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. Production of 3-Hydroxyoctadecenoylcarnitinec
Catalysed by STS, SOAT2, SOAT1, CPT1A and 2 morecytosol, endoplasmic reticulum
(13Z)-eicosenoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. long-chain-fatty-acid-CoA ligase ((13Z)-eicosenoic acid)
Catalysed by STS, SOAT2, SOAT1, SLC27A2 and 7 morecytosol, endoplasmic reticulumOne of 5 routes
4,8-dimethylnonanoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. Carnitine Dimethyl Nonanoyl Transferase, Revsible, Peroxisomal
Catalysed by STS, SOAT2, SOAT1, CRAT and 1 morecytosol, endoplasmic reticulum, peroxisomeOne of 3 routes
tetradecanedioyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. Fatty Acid Beta Oxidation (C16Dc->C14Dc), Peroxisomal
Catalysed by STS, SOAT2, SOAT1, ACAA1 and 3 morecytosol, endoplasmic reticulum, peroxisome
hexadecanedioyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. Production of Hexadecanedioylcarnitine
Catalysed by STS, SOAT2, SOAT1, CPT1A and 2 morecytosol, endoplasmic reticulumOne of 2 routes
pristanoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. fatty-acid-CoA ligase
Catalysed by STS, SOAT2, SOAT1, SLC27A2cytosol, endoplasmic reticulumOne of 2 routes
undecanoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. medium-chain acyl-CoA ligase (undecylic acid)
Catalysed by STS, SOAT2, SOAT1, ACSM4 and 5 morecytosol, endoplasmic reticulumOne of 3 routes
7alpha-hydroxypregnenoloneReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. cytochrome P450 (cholesterol)
3. pregnenolone,NADPH:oxygen oxidoreductase (7alpha-hydroxylating)
Catalysed by STS, CYP11A1, CYP7B1cytosol, mitochondrial matrixOne of 2 routes
(24S)-24-hydroxycholesterol esterReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Cytochrome P450, Family 46, Subfamily A, Polypeptide 1
3. a 1-hexadecanoyl-2-acyl-sn-glycero-3-phosphocholine + (24S)-hydroxycholesterol = (24S)-24-hydroxycholesterol ester + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by STS, CYP46A1, LCATcytosol, endoplasmic reticulum
(24S)-hydroxycholesterol 3-linoleoateReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Cytochrome P450, Family 46, Subfamily A, Polypeptide 1
3. (24S)-hydroxycholesterol + 1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine = (24S)-hydroxycholesterol 3-linoleoate + 1-hexadecanoyl-sn-glycero-3-phosphocholine
Catalysed by STS, CYP46A1, LCATcytosol, endoplasmic reticulum
(5Z)-tetradecenoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. long-chain-fatty-acid-CoA ligase (physeteric acid)
Catalysed by STS, SOAT2, SOAT1, SLC27A2 and 7 morecytosol, endoplasmic reticulumOne of 8 routes
(3E)-decenoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. Fatty Acid Beta Oxidation (C12:1->C10:1), Mitochondrial
Catalysed by STS, SOAT2, SOAT1, ACADM and 3 morecytosol, endoplasmic reticulum, mitochondrial matrix
24S,25-dihydroxycholesterolReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Cytochrome P450, Family 46, Subfamily A, Polypeptide 1
3. (24S)-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = 24S,25-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by STS, CYP46A1cytosol, endoplasmic reticulum
(24S,25R)-24,26-dihydroxycholesterolReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Cytochrome P450, Family 46, Subfamily A, Polypeptide 1
3. (24S)-hydroxycholesterol + reduced [NADPH--hemoprotein reductase] + O2 = (24S,25R)-24,26-dihydroxycholesterol + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by STS, CYP46A1cytosol, endoplasmic reticulum
(2R,6)-dimethylheptanoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. acetyl-CoA C-acyltransferase (3-oxo-4(R),8-dimethyl-nonanoyl-CoA)
Catalysed by STS, SOAT2, SOAT1, HADHA and 2 morecytosol, endoplasmic reticulum, mitochondrial matrix
16alpha-hydroxydehydroepiandrosterone 3-sulfateReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. dehydroepiandrosterone 3-sulfate + H2O = 3beta-hydroxyandrost-5-en-17-one + sulfate + H(+)
3. dehydroepiandrosterone 3-sulfate + reduced [NADPH--hemoprotein reductase] + O2 = 16alpha-hydroxydehydroepiandrosterone 3-sulfate + oxidized [NADPH--hemoprotein reductase] + H2O + H(+)
Catalysed by STS, CYP3A7cytosol
(7Z)-hexadecenoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
Catalysed by STS, SOAT2, SOAT1, SLC27A2 and 7 morecytosol, endoplasmic reticulumOne of 8 routes
tricosanoyl-CoAReach from here →
1. Cholesterol-sulfate sulfohydrolase
2. Sterol O-Acyltransferase
3. long-chain-fatty-acid-CoA ligase (tricosanoic acid)
Catalysed by STS, SOAT2, SOAT1, SLC27A2 and 7 morecytosol, endoplasmic reticulumOne of 4 routes