Compound

(24S,25R)-24,26-dihydroxycholesterol

An oxysterol that is cholesterol which is substituted by hydroxy groups at positions 24S and 27 and has S-configuration at position 25.

Definition from ChEBI (CHEBI:86165), read 2026-09-23. CC BY 4.0.

CHEBI:86165ChEBI

Open in the graph

Structure

2D depiction

Class: Organic compound
Formula: C27H46O3
Mass: 418.662 g/mol
Charge: 0
InChIKey: XMULUVSUDUCTFU-QDKHZERXSA-N
SMILES: [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@@]1(C)[C@@]2([H])CC[C@]1([H])[C@H](C)CC[C@H](O)[C@@H](C)CO
Look it up: ChEBI By InChIKey

Identity from ChEBI. Not evidence.

What it touches on the way

Mechanistic reach

1 entity

1 entities reached.

0 reported hops1 assembled from the scaffold

CYP46A1ProteinUNIPROT:Q9Y6A2metabolized byInferred only16 paths16 endpoints

What the reference databases state

Statements

1 statement

1 statement · 1 reference database · Subject: (24S,25R)-24,26-dihydroxycholesterol · Sources: Rhea

Order

(24S,25R)-24,26-dihydroxycholesterol is metabolised by CYP46A1ProteinRhea RHEA:46388Inferred only

Reactions

1 reaction

(24S)-hydroxycholesterol+reduced [NADPH--hemoprotein reductase]+dioxygen(24S,25R)-24,26-dihydroxycholesterol+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP46A1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:46388CC BY 4.0Reference data

Other names

5 names

Resolves to: (24S,25R)-24,26-dihydroxycholesterol

Also called: (25S)-cholest-5-ene-3beta,24S,26-triol(25S)-cholest-5-ene-3β,24S,26-triol24S,25S-24,26-dihydroxycholesterol
Systematic name: (3beta,24S,25S)-cholest-5-ene-3,24,26-triol(3β,24S,25S)-cholest-5-ene-3,24,26-triol