Compound
7alpha-hydroxypregnenolone
A 20-oxo steroid that is pregnenolone carrying an additional hydroxy substituent at the 7α-position.
Definition from ChEBI (CHEBI:81467), read 2026-09-23. CC BY 4.0.
Structure
- Class
- Organic compound
- Formula
- C21H32O3
- Mass
- 332.484 g/mol
- Charge
- 0
- InChIKey
- UEWNVBNIVGLQPG-XXHSLLPRSA-N
- SMILES
- [H][C@]12CC[C@]3(C)[C@@H](C(C)=O)CC[C@@]3([H])[C@]1([H])[C@H](O)C=C1C[C@@H](O)CC[C@@]12C
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What the reference databases state
Chemical structure
- 7alpha-hydroxypregnenolone has the functional parent pregnenoloneCompoundChEBI CHEBI:81467Inferred only
Statements
1 statement
1 statement · 1 reference database · Subject: 7alpha-hydroxypregnenolone · Sources: Human-GEM
- pregnenolone is converted to 7alpha-hydroxypregnenoloneCompoundHuman-GEM MAR01943Inferred only
Reactions
2 reactions
proton+NADPH(4-)+dioxygen+pregnenolone7alpha-hydroxypregnenolone+water+NADP(3-)
Catalysed by CYP7B1
Reaction pageLeft to rightBalancedEC 1.14.14.29cytosol
Human-GEM MAR01943CC BY 4.0Reference data
pregnenolone+reduced [NADPH--hemoprotein reductase]+dioxygen7alpha-hydroxypregnenolone+oxidized [NADPH--hemoprotein reductase]+water+hydron
Catalysed by CYP7B1
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:46196CC BY 4.0Reference data
Other names
5 names
Resolves to: 7alpha-hydroxypregnenolone
- Also called
- (3beta,7alpha)-3,7-dihydroxypregn-5-en-20-one(3β,7α)-3,7-dihydroxypregn-5-en-20-one3beta,7alpha-Dihydroxy-5-pregnen-20-one
- Systematic name
- 3beta,7alpha-dihydroxypregn-5-en-20-one3β,7α-dihydroxypregn-5-en-20-one