Structure
Drawn to one scale across every element, so a circle here is comparable with the same circle on another page. The radii themselves are beside this.
- Atomic radius
- 140 pm
- Ionic radius (Fe³⁺)
- 64.5 pm
- Electronegativity
- 1.83 Pauling
- Class
- Element, as a monatomic cation
- Formula
- Fe
- Mass
- 55.845 g/mol
- Charge
- +3
- InChIKey
- VTLYFUHAOXGGBS-UHFFFAOYSA-N
- SMILES
- [Fe+3]
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
14 entities
14 entities reached.
0 reported hops14 assembled from the scaffold
- SLC40A1ProteinUNIPROT:Q9NP59transported byInferred only82 paths82 endpoints
- FTH1ProteinUNIPROT:P02794substrate ofInferred only45 paths45 endpoints
- iron(2+)ElementCHEBI:29033converted toInferred only30 paths3 endpoints
- CPProteinUNIPROT:P00450substrate ofInferred only25 paths25 endpoints
- STEAP3ProteinUNIPROT:Q658P3substrate ofInferred only24 paths24 endpoints
- HEPHProteinUNIPROT:Q9BQS7substrate of, transported byInferred only20 paths20 endpoints
- FXNProteinUNIPROT:Q16595substrate ofInferred only14 paths14 endpoints
- CYBRD1ProteinUNIPROT:Q53TN4substrate ofInferred only6 paths3 endpoints
- STEAP4ProteinUNIPROT:Q687X5substrate ofInferred only5 paths5 endpoints
- LIASProteinUNIPROT:O43766substrate ofInferred only4 paths4 endpoints
- FTMTProteinUNIPROT:Q8N4E7substrate ofInferred only3 paths3 endpoints
- CYB561ProteinUNIPROT:P49447substrate ofInferred only1 path1 endpoint
What the reference databases state
Statements
38 statements
38 statements · 4 reference databases · Subject: Fe(3+) · Sources: ChEBI, Human-GEM, Rhea, UniProt
- ferric ammonium citrate is converted to Fe(3+)CompoundChEBI CHEBI:31604Inferred only
- iron(2+) is converted to Fe(3+)CompoundRhea RHEA:48712Inferred only
- Fe(3+) is converted to iron(2+)CompoundRhea RHEA:11148Inferred only
- Fe(3+) is converted to iron(2+)CompoundRhea RHEA:15061Inferred only
- Fe(3+) is converted to iron(2+)CompoundRhea RHEA:28795Inferred only
- Fe(3+) is converted to iron(2+)CompoundRhea RHEA:30155Inferred only
- Fe(3+) is converted to iron(2+)CompoundRhea RHEA:48712Inferred only
- Fe(3+) is converted to iron(2+)CompoundRhea RHEA:71767Inferred only
- iron(2+) is converted to Fe(3+)CompoundHuman-GEM MAR03991Inferred only
- iron(2+) is converted to Fe(3+)CompoundHuman-GEM MAR11407Inferred only
- iron(2+) is converted to Fe(3+)CompoundRhea RHEA:11148Inferred only
- iron(2+) is converted to Fe(3+)CompoundRhea RHEA:15061Inferred only
Show the remaining 26
- iron(2+) is converted to Fe(3+)CompoundRhea RHEA:28795Inferred only
- iron(2+) is converted to Fe(3+)CompoundRhea RHEA:30155Inferred only
- ACP5 requires the cofactor Fe(3+)ProteinUniProt P13686Inferred only
- AMDHD1 requires the cofactor Fe(3+)ProteinUniProt Q96NU7Inferred only
- PPP2CA requires the cofactor Fe(3+)ProteinUniProt P67775Inferred only
- PPP3CA requires the cofactor Fe(3+)ProteinUniProt Q08209Inferred only
- PPP3CB requires the cofactor Fe(3+)ProteinUniProt P16298Inferred only
- PPP3CC requires the cofactor Fe(3+)ProteinUniProt P48454Inferred only
- Fe(3+) is a substrate of CPProteinRhea RHEA:11148Inferred only
- Fe(3+) is a substrate of CYB561ProteinRhea RHEA:30403Inferred only
- Fe(3+) is a substrate of CYB561A3ProteinRhea RHEA:30403Inferred only
- Fe(3+) is a substrate of CYB561D1ProteinRhea RHEA:30403Inferred only
- Fe(3+) is a substrate of CYB561D2ProteinRhea RHEA:30403Inferred only
- Fe(3+) is a substrate of CYBRD1ProteinRhea RHEA:30403Inferred only
- Fe(3+) is a substrate of CYBRD1ProteinHuman-GEM MAR06395Inferred only
- Fe(3+) is a substrate of FTH1ProteinRhea RHEA:11148Inferred only
- Fe(3+) is a substrate of FTMTProteinRhea RHEA:11148Inferred only
- Fe(3+) is a substrate of FXNProteinRhea RHEA:11148Inferred only
- Fe(3+) is a substrate of HEPHProteinRhea RHEA:11148Inferred only
- Fe(3+) is a substrate of HEPHL1ProteinRhea RHEA:11148Inferred only
- Fe(3+) is a substrate of LIASProteinRhea RHEA:16585Inferred only
- Fe(3+) is a substrate of STEAP2ProteinRhea RHEA:71767Inferred only
- Fe(3+) is a substrate of STEAP3ProteinRhea RHEA:71767Inferred only
- Fe(3+) is a substrate of STEAP4ProteinRhea RHEA:71767Inferred only
- Fe(3+) is transported by HEPHProteinHuman-GEM MAR09196Inferred only
- Fe(3+) is transported by SLC40A1ProteinHuman-GEM MAR09196Inferred only
Reactions
20 reactions
4iron(2+)+4proton+dioxygen4Fe(3+)+2water
Catalysed by CP or HPS3 or FXN or FTH1 or FTMT
Reaction pageLeft to rightBalancedEC 1.16.3.1extracellular space
Human-GEM MAR03991CC BY 4.0Reference data
3FADH2+2proton+deoxyhemoglobin+3dioxygenbiliverdin IXalpha+CO+3FAD+Fe(3+)+globin+3water
Reaction pageLeft to rightUnbalancedEC 1.14.14.18cytosol
Human-GEM MAR04763CC BY 4.0Reference data
CHEBI:17208+2Fe(3+)dehydroascorbic acid+2iron(2+)+2proton
Catalysed by CYBRD1
Reaction pageLeft to rightBalancedEC 1.-.-.-extracellular space
Human-GEM MAR06395CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR09096CC BY 4.0Reference data
Transported by HEPH or SLC40A1
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR09196CC BY 4.0Reference data
4iron(2+)+4proton+dioxygen4Fe(3+)+2water
Catalysed by HEPH
Reaction pageLeft to rightBalancedEC 1.16.3.1cytosol
Human-GEM MAR11407CC BY 4.0Reference data
4iron(2+)+dioxygen+4hydron4Fe(3+)+2water
Catalysed by CP or FTH1 or FXN or HEPHL1 or FTMT or HEPH
Reaction pageReversibleBalanced
Rhea RHEA:11148CC BY 4.0Reference data
Fe(3+)+ATP(4-)+waterFe(3+)+ADP(3-)+hydrogenphosphate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:12332CC BY 4.0Reference data
2iron(2+)+NAD(1-)+hydron2Fe(3+)+NADH(2-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:15061CC BY 4.0Reference data
Fe(3+)+Fe(II)-[cytochrome c]iron(2+)+Fe(III)-[cytochrome c]
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:15617CC BY 4.0Reference data
[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster]+N(6)-octanoyl-L-lysyl-[protein]+2oxidized [2Fe-2S]-[ferredoxin]+2S-adenosyl-L-methionine+4hydron[[Fe-S] cluster scaffold protein]+N(6)-[(R)-dihydrolipoyl]-L-lysyl-[protein]+4Fe(3+)+2hydrogen sulfide+25'-deoxyadenosine+2L-methionine+2reduced [2Fe-2S]-[ferredoxin]
Catalysed by LIAS
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16585CC BY 4.0Reference data
2iron(2+)+NADP(3-)+hydron2Fe(3+)+NADPH(4-)
Reaction pageDirection not assertedBalanced
Rhea RHEA:28795CC BY 4.0Reference data
Where it reaches
10 systems, 24 regions, 85 tissues, 91 transporter routes — routes, not measurements: transporters known to carry Fe(3+) are expressed there, and no source reports it arriving.
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Other names
10 names
Resolves to: Fe(3+)
- Also called
- FE (III) IONFe(III)Fe3+Ferric ionferric ironiron, ion (Fe(3+))iron, ion (Fe3+)Iron(3+)
- Systematic name
- iron(3+) ioniron(III) cation