Compound
biliverdin IXalpha
Dicarboxylate anion of biliverdin; major species at pH 7.3.
Definition from ChEBI (CHEBI:57991), read 2026-09-23. CC BY 4.0.
Structure
No depiction stored
No three-dimensional record for this entry.
- Class
- Organic compound, anion
- Formula
- C33H32N4O6
- Mass
- 580.641 g/mol
- Charge
- -2
- InChIKey
- QBUVFDKTZJNUPP-BBROENKCSA-L
- SMILES
- C=CC1=C(C)/C(=C/C2=N/C(=Cc3nc(/C=C4NC(=O)C(C)=C4C=C)c(C)c3CCC(=O)[O-])C(CCC(=O)[O-])=C2C)NC1=O
- Look it up
- ChEBIBy InChIKey
Identity from ChEBI. Not evidence.
What it touches on the way
Mechanistic reach
3 entities
3 entities reached.
What the reference databases state
Statements
13 statements
13 statements · 2 reference databases · Subject: biliverdin IXalpha · Sources: Human-GEM, Rhea
- biliverdin IXalpha is converted to (4Z,15Z)-bilirubin IXalphaCompoundRhea RHEA:15793Inferred only
- biliverdin IXalpha is converted to (4Z,15Z)-bilirubin IXalphaCompoundRhea RHEA:15797Inferred only
- biliverdin IXalpha is converted to (4Z,15Z)-bilirubin IXalphaCompoundRhea RHEA:20980Inferred only
- (4Z,15Z)-bilirubin IXalpha is converted to biliverdin IXalphaCompoundRhea RHEA:20980Inferred only
- biliverdin IXalpha is converted to bilirubin IXalphaCompoundHuman-GEM MAR08634Inferred only
- biliverdin IXalpha is converted to bilirubin IXalphaCompoundHuman-GEM MAR04764Inferred only
- biliverdin IXalpha is a substrate of BLVRAProteinRhea RHEA:15797Inferred only
- biliverdin IXalpha is a substrate of BLVRAProteinRhea RHEA:15793Inferred only
- biliverdin IXalpha is a substrate of BLVRAProteinHuman-GEM MAR04764Inferred only
- biliverdin IXalpha is a substrate of BLVRAProteinHuman-GEM MAR08634Inferred only
- biliverdin IXalpha is a substrate of BLVRBProteinHuman-GEM MAR04764Inferred only
- biliverdin IXalpha is a substrate of BLVRBProteinHuman-GEM MAR08634Inferred only
Show the remaining 1
- biliverdin IXalpha is transported by ABCB10ProteinRhea RHEA:82359Inferred only
Reactions
17 reactions
5proton+heme b+3NADPH(4-)+3dioxygenbiliverdin IXalpha+CO+iron(2+)+3water+3NADP(3-)
Reaction pageLeft to rightBalancedEC 1.14.14.18cytosol
Human-GEM MAR01450CC BY 4.0Reference data
3FADH2+2proton+deoxyhemoglobin+3dioxygenbiliverdin IXalpha+CO+3FAD+Fe(3+)+globin+3water
Reaction pageLeft to rightUnbalancedEC 1.14.14.18cytosol
Human-GEM MAR04763CC BY 4.0Reference data
biliverdin IXalpha+proton+NADH(2-)bilirubin IXalpha+NAD(+)
Reaction pageLeft to rightBalancedEC 1.3.1.24cytosol
Human-GEM MAR04764CC BY 4.0Reference data
biliverdin IXalpha+proton+NADPH(4-)bilirubin IXalpha+NADP(3-)
Reaction pageLeft to rightBalancedEC 1.5.1.30, 1.3.1.24cytosol
Human-GEM MAR08634CC BY 4.0Reference data
biliverdin IXalpha+sodium(1+)biliverdin IXalpha+sodium(1+)
Reaction pageReversibleBalancedEC 3.1.2.2cytosol, extracellular space
Human-GEM MAR10006CC BY 4.0Reference data
Reaction pageReversibleBalance undeterminableextracellular space
Human-GEM MAR10205CC BY 4.0Reference data
CHEBI:57899+oxidized 2[4Fe-4S]-[ferredoxin]biliverdin IXalpha+reduced 2[4Fe-4S]-[ferredoxin]+2hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10168CC BY 4.0Reference data
CHEBI:57437+4oxidized [2Fe-2S]-[ferredoxin]biliverdin IXalpha+4reduced [2Fe-2S]-[ferredoxin]+4hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:15309CC BY 4.0Reference data
(4Z,15Z)-bilirubin IXalpha+NADP(3-)biliverdin IXalpha+NADPH(4-)+hydron
Catalysed by BLVRA
Reaction pageRight to leftBalanced
Rhea RHEA:15793CC BY 4.0Reference data
(4Z,15Z)-bilirubin IXalpha+NAD(1-)biliverdin IXalpha+NADH(2-)+hydron
Catalysed by BLVRA
Reaction pageRight to leftBalanced
Rhea RHEA:15797CC BY 4.0Reference data
CHEBI:57439+2oxidized [2Fe-2S]-[ferredoxin]biliverdin IXalpha+2reduced [2Fe-2S]-[ferredoxin]+2hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:16377CC BY 4.0Reference data
2(4Z,15Z)-bilirubin IXalpha+dioxygen2biliverdin IXalpha+2water
Reaction pageDirection not assertedBalanced
Rhea RHEA:20980CC BY 4.0Reference data
Where it reaches
1 system, 1 region, 1 tissue, 1 transporter route — routes, not measurements: transporters known to carry biliverdin IXalpha are expressed there, and no source reports it arriving.
Loading the model…
Other names
1 name
Resolves to: biliverdin IXalpha
- Also called
- biliverdin dianion