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Proteins/UNIPROT:Q3SY69
Mitochondrial 10-formyltetrahydrofolate dehydrogenase that catalyzes the NADP(+)-dependent conversion of 10-formyltetrahydrofolate to tetrahydrofolate and carbon dioxide..
Function from UniProtKB (Q3SY69), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
9 statements
9 statements · 5 reference databases · Subject: ALDH1L2 · Sources: Hetionet, Human-GEM, Reactome, Rhea, WikiPathways
3 reactions
10-formyltetrahydrofolic acid+water+NADP(3-)carbon dioxide+proton+NADPH(4-)+5,6,7,8-tetrahydrofolic acid
Catalysed by ALDH1L2 or ALDH1L1
Reaction pageLeft to rightBalancedEC 1.5.1.6cytosol
Human-GEM MAR04336CC BY 4.0Reference data
3 names
Resolves to: ALDH1L2
Reaction pageLeft to rightBalancedEC 1.5.1.6cytosol
Human-GEM MAR08758CC BY 4.0Reference data
(6R)-10-formyltetrahydrofolate+NADP(3-)+water(6S)-5,6,7,8-tetrahydrofolate+carbon dioxide+NADPH(4-)+hydron
Catalysed by ALDH1L1 or ALDH1L2
Reaction pageLeft to rightBalanced
Rhea RHEA:10180CC BY 4.0Reference data