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Proteins/UNIPROT:Q15326
Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Binds non-specifically to dsDNA. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth..
(Microbial infection) Inhibits Epstein-Barr virus EBNA2-mediated transcriptional activation and host cell proliferation, through direct interaction..
Function from UniProtKB (Q15326), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
92 statements
92 statements · 3 reference databases · Subject: ZMYND11 · Sources: gene ontology, Hetionet, WikiPathways
5 names
Resolves to: ZMYND11