Proteins/UNIPROT:Q9Y2Y8

PRG3

ProteinUNIPROT:Q9Y2Y8

Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP. In vitro, stimulates neutrophil superoxide production and IL8 release, and histamine and leukotriene C4 release from basophils..

Function from UniProtKB (Q9Y2Y8), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

11 statements

11 statements · 4 reference databases · Subject: PRG3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

SAA2-SAA4 covaries with PRG3ProteinHetionet hetionet:covaries:100528017-10394Inferred only
SLC6A20 covaries with PRG3ProteinHetionet hetionet:covaries:10394-54716Inferred only
SORCS2 covaries with PRG3ProteinHetionet hetionet:covaries:10394-57537Inferred only
PRG3 participates in Affected pathways in Duchenne muscular dystrophyPathwayWikiPathways WP5356Inferred only
PRG3 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
PRG3 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
PRG3 participates in Network map of SARS CoV 2 signalingPathwayWikiPathways WP5115Inferred only
PRG3 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only
PRG3 participates in Pathogenesis of SARS CoV 2 mediated by nsp9 nsp10 complexPathwayWikiPathways WP4884Inferred only
PRG3 regulates negative regulation of translationBiological processgene ontology Q9Y2Y8|GO:0017148Inferred only
PRG3 regulates positive regulation of interleukin-8 productionBiological processgene ontology Q9Y2Y8|GO:0032757Inferred only

Other names

4 names

Resolves to: PRG3

Also called: Eosinophil major basic protein homologMBPHPrepro-major basic protein homologPrepro-MBPH

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