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Proteins/UNIPROT:P11168
Facilitative hexose transporter that mediates the transport of glucose, fructose and galactose. Likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of beta cells. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney. Also able to mediate the transport of dehydroascorbate and urate..
Function from UniProtKB (P11168), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
4 rows
64 statements
64 statements · 8 reference databases · Subject: SLC2A2 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
9 reactions
beta-D-fructosebeta-D-fructose
Transported by SLC2A9 or SLC2A11 or SLC2A8 or SLC2A5 or SLC2A2 or SLC2A7
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04321CC BY 4.0Reference data
3 names
Resolves to: SLC2A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04858CC BY 4.0Reference data
Transported by SLC2A3 or SLC2A1 or SLC2A2
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04973CC BY 4.0Reference data
Transported by SLC2A3 or SLC2A9 or SLC2A1 or SLC2A11 or SLC2A8 or SLC2A5 or SLC2A12 or SLC2A6 or SLC2A2 or SLC2A14 or SLC2A4 or SLC2A7 and 1 more alternative
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05029CC BY 4.0Reference data
Transported by SLC2A2 or SLC2A3
Reaction pageDirection not assertedBalanced
Rhea RHEA:34915CC BY 4.0Reference data
Transported by SLC2A2 or SLC29A2 or SLC17A1 or SLC29A3 or SLC2A9 or SLC22A7
Reaction pageReversibleBalanced
Rhea RHEA:60368CC BY 4.0Reference data
Transported by SLC2A2 or SLC2A5 or SLC2A7 or SLC2A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:60372CC BY 4.0Reference data
Transported by SLC2A10 or SLC2A1 or SLC2A2 or SLC2A3 or SLC2A4 or SLC2A7 or SLC2A12 or SLC2A14 or SLC2A11 or SLC2A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:60376CC BY 4.0Reference data
L-dehydroascorbateL-dehydroascorbate
Transported by SLC2A2 or SLC2A14 or SLC2A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:60380CC BY 4.0Reference data