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Proteins/UNIPROT:P22732
Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of 2-deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine (By similarity). Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose (By similarity). Required for the development of high blood pressure in response to high dietary fructose intake (By similarity)..
Function from UniProtKB (P22732), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
26 statements
26 statements · 8 reference databases · Subject: SLC2A5 · Sources: Bgee, gene ontology, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
3 reactions
beta-D-fructosebeta-D-fructose
Transported by SLC2A9 or SLC2A11 or SLC2A8 or SLC2A5 or SLC2A2 or SLC2A7
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04321CC BY 4.0Reference data
4 names
Resolves to: SLC2A5
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05029CC BY 4.0Reference data
Transported by SLC2A2 or SLC2A5 or SLC2A7 or SLC2A8
Reaction pageDirection not assertedBalanced
Rhea RHEA:60372CC BY 4.0Reference data