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Proteins/UNIPROT:P11166
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors (By similarity). Required for mesendoderm differentiation (By similarity)..
Function from UniProtKB (P11166), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 1 · transported by
1 compound
1 compound.
0 reported routes1 assembled route
7 rows
122 statements
122 statements · 7 reference databases · Subject: SLC2A1 · Sources: Bgee, Hetionet, Human Protein Atlas, Human-GEM, Reactome, Rhea, WikiPathways
8 reactions
alpha-D-galactosealpha-D-galactose
Transported by SLC2A3 or SLC2A1 or SLC2A2 or SLC2A10
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR04858CC BY 4.0Reference data
Transported by SLC2A3 or SLC2A1 or SLC2A2
Reaction pageReversibleBalancedcytosol, extracellular space
4 names
Resolves to: SLC2A1
Transported by SLC2A1 or SLC2A4
Reaction pageLeft to rightBalancedextracellular space, cytosol
Human-GEM MAR04996CC BY 4.0Reference data
Transported by SLC2A1
Reaction pageReversibleBalancedcytosol, endoplasmic reticulum
Human-GEM MAR05027CC BY 4.0Reference data
Transported by SLC2A3 or SLC2A9 or SLC2A1 or SLC2A11 or SLC2A8 or SLC2A5 or SLC2A12 or SLC2A6 or SLC2A2 or SLC2A14 or SLC2A4 or SLC2A7 and 1 more alternative
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR05029CC BY 4.0Reference data
Transported by SLC2A1
Reaction pageReversibleBalancedcytosol, Golgi apparatus
Human-GEM MAR07675CC BY 4.0Reference data
dehydroascorbic aciddehydroascorbic acid
Transported by SLC2A3 or SLC2A1 or SLC2A4
Reaction pageReversibleBalancedcytosol, extracellular space
Human-GEM MAR08846CC BY 4.0Reference data