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Proteins/UNIPROT:O75147
Core component of the 3M complex, a complex required to regulate microtubule dynamics and genome integrity. It is unclear how the 3M complex regulates microtubules, it could act by controlling the level of a microtubule stabilizer. Acts as a regulator of the Cul7-RING(FBXW8) ubiquitin-protein ligase, playing a critical role in the ubiquitin ligase pathway that regulates Golgi morphogenesis and dendrite patterning in brain. Required to localize CUL7 to the Golgi apparatus in neurons..
Function from UniProtKB (O75147), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
2 rows
109 statements
109 statements · 3 reference databases · Subject: OBSL1 · Sources: gene ontology, Hetionet, Reactome
2 names
Resolves to: OBSL1