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Proteins/UNIPROT:Q9H6T0
mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2..
Function from UniProtKB (Q9H6T0), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
67 statements
67 statements · 3 reference databases · Subject: ESRP2 · Sources: gene ontology, Hetionet, Reactome
3 names
Resolves to: ESRP2