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Proteins/UNIPROT:Q99748
Growth factor that supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Involved in the development of the neural crest. Might control the size of non-neuronal cell population such as haemopoietic cells. Acts by binding to its coreceptor, GFRA2, leading to autophosphorylation and activation of the RET receptor. Heparan sulfate-binding is required for signaling..
Function from UniProtKB (Q99748), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
68 statements
68 statements · 2 reference databases · Subject: NRTN · Sources: Hetionet, Reactome
1 name
Resolves to: NRTN